Stress urinary incontinence in women is a condition widely encountered in the entire world with a prevalence between 12.8% and 46.0%. Stress urinary incontinence is a public health problem causing a significant decrease in quality of life, involving social, physical, psychological, occupational and sexual suffering of patients. The minimal invasive treatment of the stress urinary incontinence (SUI) consists in fixing a suburethral polypropylene mesh (SPM) in retropubic (TVT) or transobturator (TOT) space, in order to regain the pelvic support of the urethra, with the consecutive augmentation of the pressure of urethral closing during effort. The objective of this paper is to present the advantage of SPM in the SUI treatment in the eleven years’ experience of Department of Urology Sibiu.
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The paper presents experimental results on the mechanical behaviour for a polymer based composite sandwich panel tensile and bending tested, which uses, one by one, a cellular composite core fabricated by additive manufacturing of four different types of polymeric materials: ABS (acrylonitrile butadiene styrene), PC (polycarbonate), PLA (polylactide) and CF (polylactide + 40% carbon fibre), with the thickness of 3 and 5 mm. This research focuses on comparative analysis of the core thickness increase effect on the structure’s strength. Experimental tests carried out on standardized test-pieces with specialized laboratory equipment, are highlighting similar mechanical behaviour and are showing also an increase of composite stiffness with the increase of core thickness, at the same time, the arrangement of the cellular lattice structure has a significant effect on the structural strength.
Most studies and experimental tests performed upon orthopaedic bone cements are related to their use in everyday conditions when usual wears are due to compression and fatigue. The present paper deals with some special situations occurred during the patient’s recovery after the surgery. The recovery activities and motions may induce different types of loads, like tensile, during stretching and relaxation techniques, especially in the joint insertion area. These situations are insufficiently researched, but they represent one of the main concerns of the medical staff involved in recovery and rehabilitation. Besides the study of mechanical properties for these special situations the paper proposes also a thermal analysis during preparation of the polymethylmethacrylate(PMMA) as it can be the trigger of serious health issues (necrosis, blood circulation problems, BCIS, etc.) due to the exothermic polymerization reaction. The monitoring method proposed for the temperatures developed during the polymerization may avoid the aforementioned issues.
Difficult airway management is a common situation when the anesthesiologist deals with patients with hypo pharyngeal tumors. The volume of the tumor usually covers the glottis plan and modifies the local anatomy, making the intubation process difficult or almost impossible. Intubation laryngoscopes developments are minor and adding a CCD camera at the tip of the laryngoscope is the best improvement made in our days. Today, on the market, an intubation device designed properly for the patients with extensive hypo pharyngeal tumors does not exist. The aim of the paper is to present an innovative device designed for patients with hypo pharyngeal tumors.
Polymer microstructures containing plant extracts are a novel technique used to increase the bioavailability of active agents with low aqueous solubility. Japanese knotweed (Reynoutria japonica) is an invasive plant with multiple biomedical properties. The aim of the present study was to obtain and characterize polyurethane microstructures used as a drug delivery system of a Japanese knotweed extract. The results indicate the obtaining of microstructures with an almost neutral pH, with sizes between 540 and 1134 nm, with a medium stability against the tendency to form clusters and a very good thermal stability. These first results present the potential of the obtained polyurethane microstructures as candidates for the transmembrane drug delivery of Japanese knotweed extracts, as a starting point for further bioactivity investigations.
Microfibers were obtained from organic low molecular weight compounds based on heteroaromatic and aromatic rings connected by aliphatic spacers. The obtaining of microfibers was proved by scanning electron microscopy. The deciphering of the mechanism of microfiber formation has been elucidated by X-ray diffraction, infrared spectroscopy, and atomic force microscopy measurements. By exciting with light of different wavelength, florescence microscopy revealed a specific optical response, recommending these materials for light sensing applications.
Nanocomposite materials have attracted a high interest for biomedical applications because their special properties related with structure and composition. In this paper we synthesized novel hydrogel nanocomposite materials special designed for hard tissue engineering. The nanocomposite materials are able to promote hydroxyapatite formation by alternating soaking mineralization demanded for increasing of cells biocompatibility and adhesion.
The objective of this paper is to present the thermal behavior of various PMMA/TiO2 nanocomposite for complete dentures fabrication with 3D printing technology. There have been prepared and thermally characterized polymeric composites with varied nanofiller content ranging between 0.2% and 2.5% (w/w%). The nanocomposites proved a better thermal performance than that of pure copolymer PMMA-MMA or 3D printing PMMA polymer complex matrix. A small difference in glass transition (Tg) temperature for all compounds studied was recorded.
PLA-based composites containing CF in the range 0 to 10 wt. % were prepared by melt mixing technique. The prepared composites were investigated in terms of processability, chemical structure (by Attenuated total reflectance - Fourier Transform Infrared - ATR-FT-IR analysis), thermal (Differential Scanning Calorimetry - DSC), optical properties (using UV-Vis spectrometry), barrier and migration in distilled water. Also, the behaviour of PLA based composites at sterilization was performed by examination the changes in their chemical structure. This study shows the feasibility of improving of PLA properties by using cellulose fibres, designed for flexible food packaging.
The normal development of the placenta is a major factor in the fetus’s growth and development, whilst the maternal-fetal placental vasculature is essential in this regard. During placentation, there is an ongoing process, which combines angiogenesis with vasculogenesis, as demonstrated by numerous studies, which reveal important roles of various known angiogenic factors, while other studies show the roles of different classes of factors in vascular morphogenesis nonspecific to the placenta. The method used in the case of our study is a standardized method of the Laboratory of Anatomy and Embryology, Victor Babes University of Medicine and Pharmacy, Timiºoara, for over 50 years. The making of corrosion concoction followed the recipe of the laboratory using type AGO II plastic substances, differently colored and then subjected to the corrosive action of hydrochloric acid. During the routine check outs all the pregnant woman’s were diagnosed with thrombophilia. The examination of the placental parameters - shape, weight, thickness - is important as a preliminary stage for the study of the placental architecture. The normal placental development remains a major factor in the growth and development of the fetus, and the maternal-fetal placental vasculature is essential in this regard. Placental angiogenesis has a different local component of angiogenesis, found in other anatomical regions.