Abstract
This study was focused on the synthesis of some new hybrid materials based on poly(amidoamine) dendrimer and halloysite designed for 5-Fluorouracil encapsulation. Different techniques like Spectroscopic methods (FTIR, XPS and UV-Vis) and thermogravimetric analysis were used to characterize the hybrid materials. The morphology of the hybrid materials was pointed out using Scanning Electron Microscopy ( SEM) analysis. The obtained results showed that the drug encapsulation efficiency of the hybrid materials was strongly influenced by the interactions between dendrimer-halloysite and drug molecules. Keywords: dendrimer, halloysite, 5-fluorouracil, UV-Vis, X-Ray Photoelectron Spectroscopy