Abstract
This study has been carried out to investigate a new method to improve metallic implant bioactivity for osseointegration by producing a calcium phosphate (Ca–P) surface layer using an immersion process in the Simulated Body Fluid (SBF) of Polypyrrole (PPy) and Polypyrrole/poly(sodium-4styrensulfonate) (NaPSS) conductive hybrid polymers electrochemically synthesized on Ti6Al7Nb alloy. As formed PPy/Ca-P and PPy/PSS-/Ca-P films were characterized electrochemically by Cyclic Voltammetry (CV), Tafel plots and spectroscopically using FT-IR technique. Also, in vitro cytotoxicity of these new organic/inorganic hybrids films was evaluated by yellow 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide (MTT) assay after cultivation in a primary culture of osteoblast cells. The PPy/Ca-P hybrid film showed the best electrochemical stability and the highest value of cell viability.
Keywords: Implant alloy; Conductive polymer coating; Electrochemical tests; In vitro biocompatibility