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Open Access Research Article

Operational Procedures in the Theory of the Drug Release from Chitosan Hydrogels

ANDA MIHAELA CRACIUN, GEORGIANA SERBAN, IULIA CRUMPEI, MARICEL AGOP, GABRIELA CIOCA
Published 30 Dec 2018
Pages 590–594

Abstract

We build a theoretical model based on a generalization of harmonic applications of Misner-type. It results a sine-Gordon type fractal differential equation whose elliptical solutions can describe, through a convenient choice of fractal dynamic constants, various modes of drug release. Thus, the entire class of empirical models (Higuchi, Korsmeyer-Peppas, Peppas-Sahlin) describing the drug release processes can be dispensed with.

Keywords: chitosan hydrogels; drug release; sine-Gordon

How to Cite this Article

CRACIUN, A., SERBAN, G., CRUMPEI, I., AGOP, M., & CIOCA, G. (2018). Operational Procedures in the Theory of the Drug Release from Chitosan Hydrogels. Materiale Plastice, 55(4), 590–594. https://doi.org/10.37358/MP.18.4.5080
CRACIUN A, SERBAN G, CRUMPEI I, AGOP M, CIOCA G. Operational Procedures in the Theory of the Drug Release from Chitosan Hydrogels. Materiale Plastice. 2018;55(4):590–594. doi: 10.37358/MP.18.4.5080
A. CRACIUN, G. SERBAN, I. CRUMPEI, M. AGOP, and G. CIOCA, "Operational Procedures in the Theory of the Drug Release from Chitosan Hydrogels,” Materiale Plastice, vol. 55, no. 4, pp. 590–594, 2018. doi: 10.37358/MP.18.4.5080
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