Open Access Research Article

Research on the Effect of Aortic Valve Replacement with Mechanical Prosthesis on the Evolution of Ventricular Hypertrophy in Patients with Degenerative Aortic Stenosis

MARIA RADA, DELIA MIRA BERCEANU-VADUVA, MILAN DANIEL VELIMIROVICI, SIMONA DRAGAN, BIANCA BERCEANU-VADUVA, MARCEL MIHAI BERCEANU-VADUVA, MATILDA RADULESCU, CRISTINA TUDORAN, ANA MARIA PAH, DANA EMILIA VELIMIROVICI
Published 17 Apr 2020
Pages 209–217

Abstract

Aortic valvulopathies, and especially aortic stenosis (AS), are the most common valvular disorders. Untreated, 50% of patients with severe AS will die within 2-3 years from the onset of symptomatology. The standard treatment consists in the surgical replacement of the aortic valve with mechanical or biological prosthesis. 40 patients were included in the study after replacement of the aortic valve with double disc mechanical prosthesis for severe degenerative AS. The disks of the prosthesis are made of pyrolytic carbon characterized by extreme hardness, which provides wear protection over the years. The ring is composed of a graphite substrate coated with pyrolytic carbon and attached to a suture collar made of polyethylene (polytetrafluoroethylene - PTFE) or polyester (Dacron® or Teflon®). This study evaluates mass regression and left ventricular mass index at three months and one year postoperatively. The regression of the left ventricular mass at 3 months after the surgery is 25.86%, and at one year after the surgery this regression was reduced - 15.11%. The regression of the mass of the left ventricle and especially the premature regression, correlated with the degree of hypertrophy of the left ventricle preoperatively, highlight the beneficial effect of the double disc mechanical prosthesis.

Keywords: carbon pyrolite; Dacron; mechanical prosthesis; degenerative aortic stenosis; left ventricular hypertrophy

How to Cite this Article

RADA, M., BERCEANU-VADUVA, D., VELIMIROVICI, M., DRAGAN, S., BERCEANU-VADUVA, B., BERCEANU-VADUVA, M., RADULESCU, M., TUDORAN, C., PAH, A., & VELIMIROVICI, D. (2020). Research on the Effect of Aortic Valve Replacement with Mechanical Prosthesis on the Evolution of Ventricular Hypertrophy in Patients with Degenerative Aortic Stenosis. Materiale Plastice, 57(1), 209–217. https://doi.org/10.37358/MP.20.1.5329
RADA M, BERCEANU-VADUVA D, VELIMIROVICI M, DRAGAN S, BERCEANU-VADUVA B, BERCEANU-VADUVA M, RADULESCU M, TUDORAN C, PAH A, VELIMIROVICI D. Research on the Effect of Aortic Valve Replacement with Mechanical Prosthesis on the Evolution of Ventricular Hypertrophy in Patients with Degenerative Aortic Stenosis. Materiale Plastice. 2020;57(1):209–217. doi: 10.37358/MP.20.1.5329
M. RADA, D. BERCEANU-VADUVA, M. VELIMIROVICI, S. DRAGAN, B. BERCEANU-VADUVA, M. BERCEANU-VADUVA, M. RADULESCU, C. TUDORAN, A. PAH, and D. VELIMIROVICI, "Research on the Effect of Aortic Valve Replacement with Mechanical Prosthesis on the Evolution of Ventricular Hypertrophy in Patients with Degenerative Aortic Stenosis,” Materiale Plastice, vol. 57, no. 1, pp. 209–217, 2020. doi: 10.37358/MP.20.1.5329
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