Abstract
The poly(betaines) have been still intensively studied due to them biomedical potential. In the present work, two poly(carboxybetaines) derived from poly(4-vinylpyridine) P4VP that have methylene (P4VPB-1) or ethylene (P4VPB-2) spacer between N+ and COO- groups were investigated in order to evaluate its physico-chemical properties in aqueous salted solutions with NaCl or CaCl2. The values of refractive index increment dn/dc, weight-average molecular weight Mw, hydrodynamic radius Rh, and particle size distribution depend on the solvent type and balance between molecular forces as refractometric and laser light scattering measurements showed.
Keywords: differential refractometry; laser light scattering; poly(carboxybetaine)