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Open Access Research Article

Composite Particles Gel - Alg – Apatite for Bone Tissue Regeneration

DANIELA Petre, SERGIU Cecoltan, ANDRADA Serafim, ADRIANA Lungu, DIANA MARIA Dragusin, ELIZA GETA Stan, CATALIN Tucureanu, EUGENIU Vasile, AURORA Salageanu, MIRCEA Istodorescu, HORIA IOVU, IZABELA CRISTINA STANCU
DOI Not yet assigned
Published 30 Jun 2016
Pages 269–272

Abstract

This paper reports the fabrication of spherical particles developed as bone tissue regenerative biomaterials. Inspired by the extracellular matrix of hard tissues, the particles were generated through the mineral loading of a macromolecular matrix consisting in a bicomponent hydrogel (interpenetrated polymer networks based on gelatin and alginate). The study describes the effects of the peptide-polysaccharide ratio on the morpho-structural features, water affinity, and interaction with MG-63 osteoblast-like cells.

Keywords: spherical particles; biopolymers; hydroxyapatite; bone regeneration

How to Cite this Article

Petre, D., Cecoltan, S., Serafim, A., Lungu, A., Dragusin, D., Stan, E., Tucureanu, C., Vasile, E., Salageanu, A., Istodorescu, M., IOVU, H., & STANCU, I. (2016). Composite Particles Gel - Alg – Apatite for Bone Tissue Regeneration. Materiale Plastice, 53(2), 269–272.
Petre D, Cecoltan S, Serafim A, Lungu A, Dragusin D, Stan E, Tucureanu C, Vasile E, Salageanu A, Istodorescu M, IOVU H, STANCU I. Composite Particles Gel - Alg – Apatite for Bone Tissue Regeneration. Materiale Plastice. 2016;53(2):269–272.
D. Petre, S. Cecoltan, A. Serafim, A. Lungu, D. Dragusin, E. Stan, C. Tucureanu, E. Vasile, A. Salageanu, M. Istodorescu, H. IOVU, and I. STANCU, "Composite Particles Gel - Alg – Apatite for Bone Tissue Regeneration,” Materiale Plastice, vol. 53, no. 2, pp. 269–272, 2016.
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