Abstract
Obstructive sleep apnoea (OSA) is the most common sleep-related breathing disorder that is increasingly recognized as a serious public health issue. The treatment management is determined by the severity of the syndrome. Oral appliances (OAs) are increasingly advocated as a treatment option for mild/moderate obstructive sleep apnoea (OSA). The aim of this paper was to present the two main treatment solutions for OSAS through custom oral appliances made in dental laboratory and to systematically review the available studies in the literature on the efficacy of OAs. Keywords: Obstructive sleep apnea, Oral Appliances, Heat-curing Acrylic resins, Mandible advancement device, Thermoforming method