Abstract
According to gestational age, two groups were formed: group A (abortion) formed of 19 patients diagnosed with risk of abortion (gestational age < 23 weeks and 6 days) and group B (birth) formed of 32 patients diagnosed with risk of premature birth (gestational age > 24 weeks). We were interested in detecting adverse reactions and complications related to the use of cerclage pessaries and also to determine if this procedure is efficient in preventing premature birth. In addition to the clinical part of this study, we evaluated the mechanism of interaction of the cerclage pessaries with the fluids and the vaginal mucosa by analyzing the structure, design and surface of these devices. Cerclage pessaries are efficient in preventing premature birth. In order to decrease the number and severity of the adverse reaction related to the use of these intra-vaginal devices regular follow-up visits are indicated. Re-sterilization by ethylene oxide procedure of vaginal pessaries is prohibited because it severely modifies the surface of these apparatuses.
Keywords: cerclage pessary; preterm delivery; adverse reactions; polymeric surface