Polymer Membranes for Selective Separation of Ionizing Forms of TPPS4 as Drug Photodynamic Therapy

Simionescu, Stefania; Teodorescu, Sofia; Ion, Rodica; Nechifor, Gheorghe

Open Access Research Article

Polymer Membranes for Selective Separation of Ionizing Forms of TPPS4 as Drug Photodynamic Therapy

Stefania Simionescu, Sofia Teodorescu, Rodica Mariana Ion, Gheorghe Nechifor

DOI Not yet assigned

Published 30 Jun 2016

Issue Vol. 53, No. 2

Pages 194–197

Abstract

In this paper, some of the ionized forms and aggregated forms of tetrasulphonated porphyrin TPPS4, have been separated by passing it through a composite polymer membranes of polysulfone type with N-methyl-pyrolidone and magnetite. The aqueous solutions of TPPS4 at different pH values have been prepared, characterized and passed through the membrane, leading to the conclusion that the acidic or alkaline solutions have been transformed into neutral form with certain therapeutic properties in photodynamic therapy.

Keywords: TPPS4; polysulfone membrane; ionization; aggregation

How to Cite this Article

Simionescu, S., Teodorescu, S., Ion, R., & Nechifor, G. (2016). Polymer Membranes for Selective Separation of Ionizing Forms of TPPS4 as Drug Photodynamic Therapy. Materiale Plastice, 53(2), 194–197.

Simionescu S, Teodorescu S, Ion R, Nechifor G. Polymer Membranes for Selective Separation of Ionizing Forms of TPPS4 as Drug Photodynamic Therapy. Materiale Plastice. 2016;53(2):194–197.

S. Simionescu, S. Teodorescu, R. Ion, and G. Nechifor, "Polymer Membranes for Selective Separation of Ionizing Forms of TPPS4 as Drug Photodynamic Therapy,” Materiale Plastice, vol. 53, no. 2, pp. 194–197, 2016.

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