Abstract
The main goal of this study was to investigate the capacity of dendritic polymers to encapsulate the antitumoral drug (5-fluorouracil) using non-covalent methods. As nanoscale containers four polyamidoamine dendrimers (PAMAM) types of different generations were used. The antitumoral drug encapsulation efficiency of these dendrimers was pointed out using different methods like FTIR Spectroscopy, X-Ray Photoelectron Spectroscopy (XPS) and Thermogravimetric analysis (TGA). The obtained results showed that the dendrimers generation exhibits a strong influence on the 5-fluorouracil encapsulation. Keywords: dendrimer, antitumoral drug, FTIR analysis, X-Ray Photoelectron Spectroscopy