Abstract
Collagene-based nanocomposite membrane films were obtained by dispersing nanohybrides formed by modifying a layered silicate with quebracho and methylene blue in a collagen-gel matrix. TGA and XRD analyses proved the intercalation of active substances between the silicate layers. Thermal stability of the binary nanohybrides decreases with the increase of active substance content. Nanocomposites showed an improved thermal stability compared to collagen. Modifying the silicate with active substances influences the hydrophilicity of final nanocomposite by reducing the water vapour adsorption. Although the methylene blue is a disinfectant, it influences negatively the growth and development of the fibroblasts hence it is inappropriate for use in case of an open lesion. Quebracho is biocompatible and has a biostimulating effect on the growth and development of the fibroblasts, bioactive films thus obtained being good antiseptic and regenerating patches. Keywords: nanocomposites, montmorillonite, collagen, methylene blue, quebracho