Effects of Marine Drug Propylene Glycol Alginate Sodium Sulfate on Glucose and Lipid Metabolism in Mice

Liang, Haiyue; Liu, Qun; Xiu, Yonghong

Haiyue Liang, Qun Liu, Yonghong Xiu

Effects of Marine Drug Propylene Glycol Alginate Sodium Sulfate on Glucose and Lipid Metabolism in Mice

Abstract:
Previous studies have shown that marine drug propylene glycol alginate sodium sulfate (PSS) plays important roles in human diseases. This study mainly explored the effects of PSS on hyperglycemia and hyperlipidemia in diabetic db/db mouse models. The db/db mice were randomly divided into 5 groups (n=12), which were model control group (distilled water), positive control group (metformin), PSS low, medium, and high dose groups (PSS25, PSS50, PSS100) and normal control group (C57/BL, distilled water). The mice in each group had free diet and water for 90 days. During the experiment, food intake was recorded every day and body weight was recorded weekly. In addition, fasting blood glucose and glycosylated hemoglobin levels were measured regularly. Finally, the contents of triglyceride (TG), low-density lipoprotein (LDL-c), high-density lipoprotein (HDL-c) and total cholesterol (TC) in the serum of mice were determined. PSS can significantly reduce fasting blood glucose and glycosylated hemoglobin levels in db/db mice, and improve insulin sensitivity. Moreover, PSS can reduce the fat accumulation of db/db mice and significantly improve the blood lipid level of db/db mice. PSS can significantly improve the symptoms of glucose and lipid metabolism disorders in db/db mice.

Keywords:
marine drug; propylene glycol alginate sodium sulfate; glucose and lipid metabolism; mice

Issue: 2021 Volume 58, Issue 2

Pages: 150-154

Publication date: 2021/7/5

https://doi.org/10.37358/MP.21.2.5486

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
LIANG, H., LIU, Q., XIU, Y., Effects of Marine Drug Propylene Glycol Alginate Sodium Sulfate on Glucose and Lipid Metabolism in Mice, Mater. Plast., 58(2), 2021, 150-154. https://doi.org/10.37358/MP.21.2.5486

Vancouver
Liang H, Liu Q, Xiu Y. Effects of Marine Drug Propylene Glycol Alginate Sodium Sulfate on Glucose and Lipid Metabolism in Mice. Mater. Plast.[internet]. 2021 Apr;58(2):150-154. Available from: https://doi.org/10.37358/MP.21.2.5486

APA 6th edition
Liang, H., Liu, Q. & Xiu, Y. (2021). Effects of Marine Drug Propylene Glycol Alginate Sodium Sulfate on Glucose and Lipid Metabolism in Mice. Materiale Plastice, 58(2), 150-154. https://doi.org/10.37358/MP.21.2.5486

Harvard
Liang, H., Liu, Q., Xiu, Y. (2021). 'Effects of Marine Drug Propylene Glycol Alginate Sodium Sulfate on Glucose and Lipid Metabolism in Mice', Materiale Plastice, 58(2), pp. 150-154. https://doi.org/10.37358/MP.21.2.5486

IEEE
H. Liang, Q. Liu, Y. Xiu, "Effects of Marine Drug Propylene Glycol Alginate Sodium Sulfate on Glucose and Lipid Metabolism in Mice". Materiale Plastice, vol. 58, no. 2, pp. 150-154, 2021. [online]. https://doi.org/10.37358/MP.21.2.5486

Text
Haiyue Liang, Qun Liu, Yonghong Xiu,
Effects of Marine Drug Propylene Glycol Alginate Sodium Sulfate on Glucose and Lipid Metabolism in Mice,
Materiale Plastice,
Volume 58, Issue 2,
2021,
Pages 150-154,
ISSN 2668-8220,
https://doi.org/10.37358/MP.21.2.5486.
(https://revmaterialeplastice.ro/Articles.asp?ID=5486)
Keywords: marine drug; propylene glycol alginate sodium sulfate; glucose and lipid metabolism; mice

RIS
TY - JOUR
T1 - Effects of Marine Drug Propylene Glycol Alginate Sodium Sulfate on Glucose and Lipid Metabolism in Mice
A1 - Liang, Haiyue
A2 - Liu, Qun
A3 - Xiu, Yonghong
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2021
VL - 58
IS - 2
SP - 150
EP - 154
UR - https://doi.org/10.37358/MP.21.2.5486
KW - marine drug
KW - propylene glycol alginate sodium sulfate
KW - glucose and lipid metabolism
KW - mice
ER -

BibTex
@article{MatPlast2021P150,
author = {Liang Haiyue and Liu Qun and Xiu Yonghong},
title = {Effects of Marine Drug Propylene Glycol Alginate Sodium Sulfate on Glucose and Lipid Metabolism in Mice},
journal = {Materiale Plastice},
volume = {58},
number = {2},
pages = {150-154},
year = {2021},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.21.2.5486},
url = {https://revmaterialeplastice.ro/Articles.asp?ID=5486}
}

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