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Materiale Plastice
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https://doi.org/10.37358/Mat.Plast.1964

OSIM Nr. R102356
ISSN Print 0025-5289
ISSN Online 2668-8220
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Materiale Plastice (Mater. Plast.), Year 2020, Volume 57, Issue 2, 131-139

https://doi.org/10.37358/MP.20.2.5359

MADALINA ANCA MOLDOVAN (LAZAR)ORCID LOGO, ADINA BIANCA BOSCA ORCID LOGO, CALIN RARES ROMAN ORCID LOGO, HORATIU ROTARU ORCID LOGO, CRISTINA PREJMEREAN ORCID LOGO, DOINA PRODAN ORCID LOGO, PAUL BERE ORCID LOGO, COSMIN COSMA ORCID LOGO, DANA FESTILA ORCID LOGO, MIRCEA CONSTANTIN GHERGIE ORCID LOGO

Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants


Abstract:
Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implantslthough autologous bone graft is the gold standard in bone reconstruction, the limited volume, the morbidity associated with the donor site, the dificult modelling of complex forms and the unpredictable rate of resorption fuel the researches towards the development of alloplastic materials as bone substitutes.A new fiber reinforced composite (FRC) was developed using 35% combination of monomers bisphenol A glycidylmethacrylate , urethane dimethacrylate , triethylene glycol dimethacrylate , ) and 65% E-glass fibers (300 g/mp). Sixteen (n=16) male Wistar rats were used for the study. The experimental group (n=12) received intrafemoral implants of FRC. The control group (n=4) received intrafemoral titanium implants. After one month and three months respectively, tissues adjacent to implants were histologically evaluated. The intensity of the bone tissue inflammatory reaction, as well as the presence of the osteoblasts and the newly formed bone on the implant surface were the main criteria assessed. The FRC material determined a similar tissue reaction to Ti specimens, at one- and three-months follow-up. Both materials, inserted in the medullary canal, were surrounded by a fibrous connective tissue capsule, which, as time passed, underwent intramembranous ossification process. Fiber reinforced composite may be considered a promising alternative to titanium implants in critical size defects reconstruction.


Keywords:
fiber-reinforced composite; biocompatibility assessment in vivo

Issue: 2020 Volume 57, Issue 2
Pages: 131-139
Publication date: 01/07/2019
https://doi.org/10.37358/MP.20.2.5359
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This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
MOLDOVAN (LAZAR), M.A., BOSCA, A.B., ROMAN, R., ROTARU, H., PREJMEREAN, C., PRODAN, D., BERE, P., COSMA, C., FESTILA, D., GHERGIE, M.C., Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants, Mater. Plast., 57(2), 2020, 131-139.

Vancouver
Moldovan (Lazar) MA, Bosca aB, Roman R, Rotaru H, Prejmerean C, Prodan D, Bere P, Cosma C, Festila D, Ghergie MC. Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants. Mater. Plast.[internet]. 2020 Apr;57(2):131-139. Available from: https://doi.org/10.37358/MP.20.2.5359


APA 6th edition
Moldovan (Lazar), M.A., Bosca, a.B., Roman, R., Rotaru, H., Prejmerean, C., Prodan, D.,... Ghergie, M.C. (2020). Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants. Materiale Plastice, 57(2), 131-139. https://doi.org/10.37358/MP.20.2.5359


Harvard
Moldovan (Lazar), M.A., Bosca, a.B., Roman, R., Rotaru, H., Prejmerean, C., Prodan, D., Bere, P., Cosma, C., Festila, D., Ghergie, M.C. (2020). 'Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants', Materiale Plastice, 57(2), pp. 131-139. https://doi.org/10.37358/MP.20.2.5359


IEEE
M.A. Moldovan(Lazar), a.B. Bosca, R. Roman, H. Rotaru, C. Prejmerean, D. Prodan, P. Bere, C. Cosma, D. Festila, M.C. Ghergie, "Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants". Materiale Plastice, vol. 57, no. 2, pp. 131-139, 2020. [online]. https://doi.org/10.37358/MP.20.2.5359


Text
Madalina Anca Moldovan (Lazar),adina Bianca Bosca, Rares Roman, Horatiu Rotaru, Cristina Prejmerean, Doina Prodan, Paul Bere, Cosmin Cosma, Dana Festila, Mircea Constantin Ghergie,
Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants,
Materiale Plastice,
Volume 57, Issue 2,
2020,
Pages 131-139,
ISSN 2668-8220,
https://doi.org/10.37358/MP.20.2.5359.
(https://revmaterialeplastice.ro/Articles.asp?ID=5359)
Keywords: fiber-reinforced composite; biocompatibility assessment in vivo


RIS
TY - JOUR
T1 - Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants
A1 - Moldovan (Lazar), Madalina Anca
A2 - Bosca, adina Bianca
A3 - Roman, Rares
A4 - Rotaru, Horatiu
A5 - Prejmerean, Cristina
A6 - Prodan, Doina
A7 - Bere, Paul
A8 - Cosma, Cosmin
A9 - Festila, Dana
A10 - Ghergie, Mircea Constantin
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2020
VL - 57
IS - 2
SP - 131
EP - 139
UR - https://doi.org/10.37358/MP.20.2.5359
KW - fiber-reinforced composite
KW - biocompatibility assessment in vivo
ER -


BibTex
@article{MatPlast2020P131,
author = {Moldovan (Lazar) Madalina Anca and Bosca adina Bianca and Roman Rares and Rotaru Horatiu and Prejmerean Cristina and Prodan Doina and Bere Paul and Cosma Cosmin and Festila Dana and Ghergie Mircea Constantin},
title = {Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants},
journal = {Materiale Plastice},
volume = {57},
number = {2},
pages = {131-139},
year = {2020},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.20.2.5359},
url = {https://revmaterialeplastice.ro/Articles.asp?ID=5359}
}
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