Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants

Moldovan (Lazar), Madalina Anca; Bosca, adina Bianca; Roman, Rares; Rotaru, Horatiu; Prejmerean, Cristina; Prodan, Doina; Bere, Paul; Cosma, Cosmin; Festila, Dana; Ghergie, Mircea Constantin

MADALINA ANCA MOLDOVAN (LAZAR), ADINA BIANCA BOSCA , CALIN RARES ROMAN , HORATIU ROTARU , CRISTINA PREJMEREAN , DOINA PRODAN , PAUL BERE , COSMIN COSMA , DANA FESTILA , MIRCEA CONSTANTIN GHERGIE

Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants

Abstract:
Although autologous bone graft is the gold standard in bone reconstruction, the limited volume, the morbidity associated with the donor site, the dificult modelling of complex forms and the unpredictable rate of resorption fuel the researches towards the development of alloplastic materials as bone substitutes.A new fiber reinforced composite (FRC) was developed using 35% combination of monomers bisphenol A glycidylmethacrylate , urethane dimethacrylate , triethylene glycol dimethacrylate , ) and 65% E-glass fibers (300 g/mp). Sixteen (n=16) male Wistar rats were used for the study. The experimental group (n=12) received intrafemoral implants of FRC. The control group (n=4) received intrafemoral titanium implants. After one month and three months respectively, tissues adjacent to implants were histologically evaluated. The intensity of the bone tissue inflammatory reaction, as well as the presence of the osteoblasts and the newly formed bone on the implant surface were the main criteria assessed. The FRC material determined a similar tissue reaction to Ti specimens, at one- and three-months follow-up. Both materials, inserted in the medullary canal, were surrounded by a fibrous connective tissue capsule, which, as time passed, underwent intramembranous ossification process. Fiber reinforced composite may be considered a promising alternative to titanium implants in critical size defects reconstruction.

Keywords:
fiber-reinforced composite; biocompatibility assessment in vivo

Issue: 2020 Volume 57, Issue 2

Pages: 131-139

Publication date: 2019/7/1

https://doi.org/10.37358/MP.20.2.5359

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
MOLDOVAN (LAZAR), M.A., BOSCA, A.B., ROMAN, R., ROTARU, H., PREJMEREAN, C., PRODAN, D., BERE, P., COSMA, C., FESTILA, D., GHERGIE, M.C., Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants, Mater. Plast., 57(2), 2020, 131-139. https://doi.org/10.37358/MP.20.2.5359

Vancouver
Moldovan (Lazar) MA, Bosca aB, Roman R, Rotaru H, Prejmerean C, Prodan D, Bere P, Cosma C, Festila D, Ghergie MC. Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants. Mater. Plast.[internet]. 2020 Apr;57(2):131-139. Available from: https://doi.org/10.37358/MP.20.2.5359

APA 6th edition
Moldovan (Lazar), M.A., Bosca, a.B., Roman, R., Rotaru, H., Prejmerean, C., Prodan, D.,... Ghergie, M.C. (2020). Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants. Materiale Plastice, 57(2), 131-139. https://doi.org/10.37358/MP.20.2.5359

Harvard
Moldovan (Lazar), M.A., Bosca, a.B., Roman, R., Rotaru, H., Prejmerean, C., Prodan, D., Bere, P., Cosma, C., Festila, D., Ghergie, M.C. (2020). 'Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants', Materiale Plastice, 57(2), pp. 131-139. https://doi.org/10.37358/MP.20.2.5359

IEEE
M.A. Moldovan(Lazar), a.B. Bosca, R. Roman, H. Rotaru, C. Prejmerean, D. Prodan, P. Bere, C. Cosma, D. Festila, M.C. Ghergie, "Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants". Materiale Plastice, vol. 57, no. 2, pp. 131-139, 2020. [online]. https://doi.org/10.37358/MP.20.2.5359

Text
Madalina Anca Moldovan (Lazar),adina Bianca Bosca, Rares Roman, Horatiu Rotaru, Cristina Prejmerean, Doina Prodan, Paul Bere, Cosmin Cosma, Dana Festila, Mircea Constantin Ghergie,
Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants,
Materiale Plastice,
Volume 57, Issue 2,
2020,
Pages 131-139,
ISSN 2668-8220,
https://doi.org/10.37358/MP.20.2.5359.
(https://revmaterialeplastice.ro/Articles.asp?ID=5359)
Keywords: fiber-reinforced composite; biocompatibility assessment in vivo

RIS
TY - JOUR
T1 - Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants
A1 - Moldovan (Lazar), Madalina Anca
A2 - Bosca, adina Bianca
A3 - Roman, Rares
A4 - Rotaru, Horatiu
A5 - Prejmerean, Cristina
A6 - Prodan, Doina
A7 - Bere, Paul
A8 - Cosma, Cosmin
A9 - Festila, Dana
A10 - Ghergie, Mircea Constantin
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2020
VL - 57
IS - 2
SP - 131
EP - 139
UR - https://doi.org/10.37358/MP.20.2.5359
KW - fiber-reinforced composite
KW - biocompatibility assessment in vivo
ER -

BibTex
@article{MatPlast2020P131,
author = {Moldovan (Lazar) Madalina Anca and Bosca adina Bianca and Roman Rares and Rotaru Horatiu and Prejmerean Cristina and Prodan Doina and Bere Paul and Cosma Cosmin and Festila Dana and Ghergie Mircea Constantin},
title = {Bone Reaction to a Newly Developed Fiber-reinforced Composite Material for Craniofacial Implants},
journal = {Materiale Plastice},
volume = {57},
number = {2},
pages = {131-139},
year = {2020},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.20.2.5359},
url = {https://revmaterialeplastice.ro/Articles.asp?ID=5359}
}

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