Subcoronary Technique for Orthotopic Implantation of Aortic Scaffold Reinforced with Polytetrafluoroethylene Strips in Sheep: A pilot Study

Hussein, Hussam Al; Hussein, Hamida Al; Harpa, Marius; Sircuta, Carmen; Cotoi, Ovidiu S.; Man, Adrian; Deac, Radu; Suciu, Horatiu; Brinzaniuc, Klara; Simionescu, Dan

Hussam Al Hussein, Hamida Al Hussein, Marius Harpa, Carmen Sircuta, Ovidiu S. Cotoi, Adrian Man, Radu Deac, Horatiu Suciu, Klara Brinzaniuc, Dan Simionescu

Subcoronary Technique for Orthotopic Implantation of Aortic Scaffold Reinforced with Polytetrafluoroethylene Strips in Sheep: A pilot Study

Abstract:
Over the time, numerous studies have been reported describing successful pulmonary valve replacement, either with xenografts or allografts, performed in sheep model. In contrast, comparable results have not been achieved yet for aortic valve replacement in orthotopic position, which involves a more difficult surgical technique, high hemodynamic demands for the implanted valve and poor survival of animals undergoing this kind of surgery. To our knowledge, in Romania, these were the first orthotopic allogeneic aortic root implantations using the subcoronary technique, carried out by our team. We established feasible perioperative, anesthetic and surgical protocols, which will be used in future studies to evaluate the in vivo functional performances of decellularized valves compared with autologous adipose derived stem cells seeded valves. Therefore, a unique research core was created, which is currently the only center of this kind in our country, by joining a multidisciplinary team consisting of biomedical engineers, cardiovascular surgeons, anesthesiologists, cardiologists, pathologists, microbiologists and veterinarians, who will continue the research activity in the field of tissue engineering and translate experimental results into clinical activity.

Keywords:
decellularized aortic roots; subcoronary technique; sheep; aortic valve implantation

Issue: 2020 Volume 57, Issue 2

Pages: 104-112

Publication date: 2019/7/1

https://doi.org/10.37358/MP.20.2.5356

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
HUSSEIN, H.A., HUSSEIN, H.A., HARPA, M., SIRCUTA, C., COTOI, O.S., MAN, A., DEAC, R., SUCIU, H., BRINZANIUC, K., SIMIONESCU, D., Subcoronary Technique for Orthotopic Implantation of Aortic Scaffold Reinforced with Polytetrafluoroethylene Strips in Sheep: A pilot Study, Mater. Plast., 57(2), 2020, 104-112. https://doi.org/10.37358/MP.20.2.5356

Vancouver
Hussein HA, Hussein HA, Harpa M, Sircuta C, Cotoi OS, Man A, Deac R, Suciu H, Brinzaniuc K, Simionescu D. Subcoronary Technique for Orthotopic Implantation of Aortic Scaffold Reinforced with Polytetrafluoroethylene Strips in Sheep: A pilot Study. Mater. Plast.[internet]. 2020 Apr;57(2):104-112. Available from: https://doi.org/10.37358/MP.20.2.5356

APA 6th edition
Hussein, H.A., Hussein, H.A., Harpa, M., Sircuta, C., Cotoi, O.S., Man, A.,... Simionescu, D. (2020). Subcoronary Technique for Orthotopic Implantation of Aortic Scaffold Reinforced with Polytetrafluoroethylene Strips in Sheep: A pilot Study. Materiale Plastice, 57(2), 104-112. https://doi.org/10.37358/MP.20.2.5356

Harvard
Hussein, H.A., Hussein, H.A., Harpa, M., Sircuta, C., Cotoi, O.S., Man, A., Deac, R., Suciu, H., Brinzaniuc, K., Simionescu, D. (2020). 'Subcoronary Technique for Orthotopic Implantation of Aortic Scaffold Reinforced with Polytetrafluoroethylene Strips in Sheep: A pilot Study', Materiale Plastice, 57(2), pp. 104-112. https://doi.org/10.37358/MP.20.2.5356

IEEE
H.A. Hussein, H.A. Hussein, M. Harpa, C. Sircuta, O.S. Cotoi, A. Man, R. Deac, H. Suciu, K. Brinzaniuc, D. Simionescu, "Subcoronary Technique for Orthotopic Implantation of Aortic Scaffold Reinforced with Polytetrafluoroethylene Strips in Sheep: A pilot Study". Materiale Plastice, vol. 57, no. 2, pp. 104-112, 2020. [online]. https://doi.org/10.37358/MP.20.2.5356

Text
Hussam Al Hussein, Hamida Al Hussein, Marius Harpa, Carmen Sircuta, Ovidiu S. Cotoi, Adrian Man, Radu Deac, Horatiu Suciu, Klara Brinzaniuc, Dan Simionescu,
Subcoronary Technique for Orthotopic Implantation of Aortic Scaffold Reinforced with Polytetrafluoroethylene Strips in Sheep: A pilot Study,
Materiale Plastice,
Volume 57, Issue 2,
2020,
Pages 104-112,
ISSN 2668-8220,
https://doi.org/10.37358/MP.20.2.5356.
(https://revmaterialeplastice.ro/Articles.asp?ID=5356)
Keywords: decellularized aortic roots; subcoronary technique; sheep; aortic valve implantation

RIS
TY - JOUR
T1 - Subcoronary Technique for Orthotopic Implantation of Aortic Scaffold Reinforced with Polytetrafluoroethylene Strips in Sheep: A pilot Study
A1 - Hussein, Hussam Al
A2 - Hussein, Hamida Al
A3 - Harpa, Marius
A4 - Sircuta, Carmen
A5 - Cotoi, Ovidiu S.
A6 - Man, Adrian
A7 - Deac, Radu
A8 - Suciu, Horatiu
A9 - Brinzaniuc, Klara
A10 - Simionescu, Dan
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2020
VL - 57
IS - 2
SP - 104
EP - 112
UR - https://doi.org/10.37358/MP.20.2.5356
KW - decellularized aortic roots
KW - subcoronary technique
KW - sheep
KW - aortic valve implantation
ER -

BibTex
@article{MatPlast2020P104,
author = {Hussein Hussam Al and Hussein Hamida Al and Harpa Marius and Sircuta Carmen and Cotoi Ovidiu S. and Man Adrian and Deac Radu and Suciu Horatiu and Brinzaniuc Klara and Simionescu Dan},
title = {Subcoronary Technique for Orthotopic Implantation of Aortic Scaffold Reinforced with Polytetrafluoroethylene Strips in Sheep: A pilot Study},
journal = {Materiale Plastice},
volume = {57},
number = {2},
pages = {104-112},
year = {2020},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.20.2.5356},
url = {https://revmaterialeplastice.ro/Articles.asp?ID=5356}
}

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