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Materiale Plastice
Cite as: Mater. Plast.
https://doi.org/10.37358/Mat.Plast.1964

OSIM Nr. R102356
ISSN Print 0025-5289
ISSN Online 2668-8220
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* Impact factor 2019: 1.517
* 5-Year IF: 1.179
* CiteScore: 2.4
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Materiale Plastice (Mater. Plast.), Year 2019, Volume 56, Issue 3, 543-547

https://doi.org/10.37358/MP.19.3.5226

Flavius Olaru, Dana Stoian, Delia Berceanu Vaduva, Alina Corpade, Florin Birsasteanu, Dan Navolan, Constantin Tudor Luca, Octavian Cretu, Adrian Carabineanu, Sorin Motoi, Florin Borcan, Marius Craina, Amadeus Dobrescu

Studies on a Levonorgestrel-Releasing Trade Plastic Device and on a Similar Polyurethane Foam Used as a Levonorgestrel Carrier


Abstract:
Hormonal Intrauterine Devices (IUD) were developed based on copper IUD with the role to release a daily amount of hormones. From a structural point of view Levonorgestrel-IUD (L-IUD) is a small T-shaped piece of plastic, which contains levonorgestrel. When compared with the oral route of L-IUD administration, it provides some advantages because it releases levonorgestrel directly into the uterus. Our aims were: (1) to compare the thickness of uterine jonctional zone (UJZ) in two groups of patients with and without inserted L-IUD, (2) to evaluate the changes in thickness of UJZ after the insertion of L-IUD in two patients with adenomyosis, and (3) to obtain and to characterize a similar T-shaped polyurethane (PU) foam used as a levonorgestrel delivery system. On the one hand, the results confirm that L-IUD is effective in thinning the UJZ and in the treatment of adenomyosis, while on the other hand, the characterization of the PU materials (Zetasizer measurements, their thermal degradation, UV-Vis spectra and skin irritation tests) revealed that this polymer can be used as a safety and prolonged levonorgestrel carrier.


Keywords:
adenomyosis; junctional zone; levonorgestrel-releasing IUD; mexametry; polymer structures;thermal behavior; Zeta potential

Issue: 2019 Volume 56, Issue 3
Pages: 543-547
Publication date: 2019/9/30
https://doi.org/10.37358/MP.19.3.5226
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
OLARU, F., STOIAN, D., VADUVA, D.B., CORPADE, A., BIRSASTEANU, F., NAVOLAN, D., LUCA, C.T., CRETU, O., CARABINEANU, A., MOTOI, S., BORCAN, F., CRAINA, M., DOBRESCU, A., Studies on a Levonorgestrel-Releasing Trade Plastic Device and on a Similar Polyurethane Foam Used as a Levonorgestrel Carrier, Mater. Plast., 56(3), 2019, 543-547.

Vancouver
Olaru F, Stoian D, Vaduva DB, Corpade A, Birsasteanu F, Navolan D, Luca CT, Cretu O, Carabineanu A, Motoi S, Borcan F, Craina M, Dobrescu A. Studies on a Levonorgestrel-Releasing Trade Plastic Device and on a Similar Polyurethane Foam Used as a Levonorgestrel Carrier. Mater. Plast.[internet]. 2019 Jul;56(3):543-547. Available from: https://doi.org/10.37358/MP.19.3.5226


APA 6th edition
Olaru, F., Stoian, D., Vaduva, D.B., Corpade, A., Birsasteanu, F., Navolan, D.,... Dobrescu, A. (2019). Studies on a Levonorgestrel-Releasing Trade Plastic Device and on a Similar Polyurethane Foam Used as a Levonorgestrel Carrier. Materiale Plastice, 56(3), 543-547. https://doi.org/10.37358/MP.19.3.5226


Harvard
Olaru, F., Stoian, D., Vaduva, D.B., Corpade, A., Birsasteanu, F., Navolan, D., Luca, C.T., Cretu, O., Carabineanu, A., Motoi, S., Borcan, F., Craina, M., Dobrescu, A. (2019). 'Studies on a Levonorgestrel-Releasing Trade Plastic Device and on a Similar Polyurethane Foam Used as a Levonorgestrel Carrier', Materiale Plastice, 56(3), pp. 543-547. https://doi.org/10.37358/MP.19.3.5226


IEEE
F. Olaru, D. Stoian, D.B. Vaduva, A. Corpade, F. Birsasteanu, D. Navolan, C.T. Luca, O. Cretu, A. Carabineanu, S. Motoi, F. Borcan, M. Craina, A. Dobrescu, "Studies on a Levonorgestrel-Releasing Trade Plastic Device and on a Similar Polyurethane Foam Used as a Levonorgestrel Carrier". Materiale Plastice, vol. 56, no. 3, pp. 543-547, 2019. [online]. https://doi.org/10.37358/MP.19.3.5226


Text
Flavius Olaru, Dana Stoian, Delia Berceanu Vaduva, Alina Corpade, Florin Birsasteanu, Dan Navolan, Constantin Tudor Luca, Octavian Cretu, Adrian Carabineanu, Sorin Motoi, Florin Borcan, Marius Craina, Amadeus Dobrescu,
Studies on a Levonorgestrel-Releasing Trade Plastic Device and on a Similar Polyurethane Foam Used as a Levonorgestrel Carrier,
Materiale Plastice,
Volume 56, Issue 3,
2019,
Pages 543-547,
ISSN 2668-8220,
https://doi.org/10.37358/MP.19.3.5226.
(https://revmaterialeplastice.ro/Articlegs.asp?ID=5226)
Keywords: adenomyosis; junctional zone; levonorgestrel-releasing IUD; mexametry; polymer structures;thermal behavior; Zeta potential


RIS
TY - JOUR
T1 - Studies on a Levonorgestrel-Releasing Trade Plastic Device and on a Similar Polyurethane Foam Used as a Levonorgestrel Carrier
A1 - Olaru, Flavius
A2 - Stoian, Dana
A3 - Vaduva, Delia Berceanu
A4 - Corpade, Alina
A5 - Birsasteanu, Florin
A6 - Navolan, Dan
A7 - Luca, Constantin Tudor
A8 - Cretu, Octavian
A9 - Carabineanu, Adrian
A10 - Motoi, Sorin
A11 - Borcan, Florin
A12 - Craina, Marius
A13 - Dobrescu, Amadeus
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2019
VL - 56
IS - 3
SP - 543
EP - 547
UR - https://doi.org/10.37358/MP.19.3.5226
KW - adenomyosis
KW - junctional zone
KW - levonorgestrel-releasing IUD
KW - mexametry
KW - polymer structures
KW - thermal behavior
KW - Zeta potential
ER -


BibTex
@article{MatPlast2019P543,
author = {Olaru Flavius and Stoian Dana and Vaduva Delia Berceanu and Corpade Alina and Birsasteanu Florin and Navolan Dan and Luca Constantin Tudor and Cretu Octavian and Carabineanu Adrian and Motoi Sorin and Borcan Florin and Craina Marius and Dobrescu Amadeus},
title = {Studies on a Levonorgestrel-Releasing Trade Plastic Device and on a Similar Polyurethane Foam Used as a Levonorgestrel Carrier},
journal = {Materiale Plastice},
volume = {56},
number = {3},
pages = {543-547},
year = {2019},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.19.3.5226},
url = {https://revmaterialeplastice.ro/Articlegs.asp?ID=5226}
}
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