ABOUT INDEXING EDITORIAL BOARD ARCHIVES AUTHOR GUIDELINES SUBMIT PAPER NEWS, EVENTS AUTHOR'S PAGE CONTACT
Materiale Plastice
Cite as: Mater. Plast.
https://doi.org/10.37358/Mat.Plast.1964

OSIM Nr. R102356
ISSN Print 0025-5289
ISSN Online 2668-8220
Journal Metrics
* Impact factor 2019: 1.517
* 5-Year IF: 1.179
* CiteScore: 2.4
* H index: 22
Materiale Plastice - Latest Issue

Latest Issue >>>
ARCHIVES
   Volume 58, 2021
   Volume 57, 2020
   Volume 56, 2019
   Volume 55, 2018
   Volume 54, 2017
   Volume 53, 2016
   Volume 52, 2015
   Volume 51, 2014
   Volume 50, 2013
   Volume 49, 2012
   Volume 48, 2011
   Volume 47, 2010
   Volume 46, 2009
   Volume 45, 2008
   Volume 44, 2007
   Volume 43, 2006
   Volume 42, 2005
   Volume 41, 2004
   Volume 40, 2003
 
<<<< back

Materiale Plastice (Mater. Plast.), Year 2019, Volume 56, Issue 2, 337-340

https://doi.org/10.37358/MP.19.2.5182

Daniela Miricescu, Daniela Gabriela Balan, Catalina Radulescu, Radu Radulescu, Iulia-Ioana Stanescu, Maria Mohora, Bogdana Virgolici, Alexandra Totan, Maria Greabu

The Antioxidant Effects of PLGA-based Nanoparticles Loaded with Vitamin E in Rats Treated with Hypercaloric Diet


Abstract:
PLGA (Poli-lactic-co-glycolic acid) nanoparticles (NPs) are curently used as drug delivery systems for many types of drugs including antioxidants such as vitamin E. The main aim of our study was to test the antioxidant effects of PLGA-vitamin E on Wistar male rats. Two groups of Wistar rats received a hypercaloric diet for 21 days: the first group received besides the hypercaloric diet a daily dose of PLGA loaded with vitamin E and the control group received only the hypercaloric diet. Spleen cellular lysate has been used to detect biomarkers of oxidative stress such as malondialdehyde, glutathione, advanced human oxidative protein and vitamin E. After 3 weeks of treatment, statistical significant changes have been detected between the two groups.


Keywords:
PLGA nanoparticles; spleen; hypercaloric diet

Issue: 2019 Volume 56, Issue 2
Pages: 337-340
Publication date: 2019/6/30
https://doi.org/10.37358/MP.19.2.5182
download pdf   Download Pdf Article
Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
MIRICESCU, D., BALAN, D.G., RADULESCU, C., RADULESCU, R., STANESCU, I., MOHORA, M., VIRGOLICI, B., TOTAN, A., GREABU, M., The Antioxidant Effects of PLGA-based Nanoparticles Loaded with Vitamin E in Rats Treated with Hypercaloric Diet, Mater. Plast., 56(2), 2019, 337-340.

Vancouver
Miricescu D, Balan DG, Radulescu C, Radulescu R, Stanescu I, Mohora M, Virgolici B, Totan A, Greabu M. The Antioxidant Effects of PLGA-based Nanoparticles Loaded with Vitamin E in Rats Treated with Hypercaloric Diet. Mater. Plast.[internet]. 2019 Apr;56(2):337-340. Available from: https://doi.org/10.37358/MP.19.2.5182


APA 6th edition
Miricescu, D., Balan, D.G., Radulescu, C., Radulescu, R., Stanescu, I., Mohora, M.,... Greabu, M. (2019). The Antioxidant Effects of PLGA-based Nanoparticles Loaded with Vitamin E in Rats Treated with Hypercaloric Diet. Materiale Plastice, 56(2), 337-340. https://doi.org/10.37358/MP.19.2.5182


Harvard
Miricescu, D., Balan, D.G., Radulescu, C., Radulescu, R., Stanescu, I., Mohora, M., Virgolici, B., Totan, A., Greabu, M. (2019). 'The Antioxidant Effects of PLGA-based Nanoparticles Loaded with Vitamin E in Rats Treated with Hypercaloric Diet', Materiale Plastice, 56(2), pp. 337-340. https://doi.org/10.37358/MP.19.2.5182


IEEE
D. Miricescu, D.G. Balan, C. Radulescu, R. Radulescu, I. Stanescu, M. Mohora, B. Virgolici, A. Totan, M. Greabu, "The Antioxidant Effects of PLGA-based Nanoparticles Loaded with Vitamin E in Rats Treated with Hypercaloric Diet". Materiale Plastice, vol. 56, no. 2, pp. 337-340, 2019. [online]. https://doi.org/10.37358/MP.19.2.5182


Text
Daniela Miricescu, Daniela Gabriela Balan, Catalina Radulescu, Radu Radulescu, Iulia-Ioana Stanescu, Maria Mohora, Bogdana Virgolici, Alexandra Totan, Maria Greabu,
The Antioxidant Effects of PLGA-based Nanoparticles Loaded with Vitamin E in Rats Treated with Hypercaloric Diet,
Materiale Plastice,
Volume 56, Issue 2,
2019,
Pages 337-340,
ISSN 2668-8220,
https://doi.org/10.37358/MP.19.2.5182.
(https://revmaterialeplastice.ro/Articlegs.asp?ID=5182)
Keywords: PLGA nanoparticles; spleen; hypercaloric diet


RIS
TY - JOUR
T1 - The Antioxidant Effects of PLGA-based Nanoparticles Loaded with Vitamin E in Rats Treated with Hypercaloric Diet
A1 - Miricescu, Daniela
A2 - Balan, Daniela Gabriela
A3 - Radulescu, Catalina
A4 - Radulescu, Radu
A5 - Stanescu, Iulia-Ioana
A6 - Mohora, Maria
A7 - Virgolici, Bogdana
A8 - Totan, Alexandra
A9 - Greabu, Maria
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2019
VL - 56
IS - 2
SP - 337
EP - 340
UR - https://doi.org/10.37358/MP.19.2.5182
KW - PLGA nanoparticles
KW - spleen
KW - hypercaloric diet
ER -


BibTex
@article{MatPlast2019P337,
author = {Miricescu Daniela and Balan Daniela Gabriela and Radulescu Catalina and Radulescu Radu and Stanescu Iulia-Ioana and Mohora Maria and Virgolici Bogdana and Totan Alexandra and Greabu Maria},
title = {The Antioxidant Effects of PLGA-based Nanoparticles Loaded with Vitamin E in Rats Treated with Hypercaloric Diet},
journal = {Materiale Plastice},
volume = {56},
number = {2},
pages = {337-340},
year = {2019},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.19.2.5182},
url = {https://revmaterialeplastice.ro/Articlegs.asp?ID=5182}
}
<<<< back
 
  Search Authors
Crossref Member Badge
 DOI  logo
 Gold Open Access | Source=http://www.plos.org/  | Author=art designer at PLoS
Creative Commons License