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Materiale Plastice
Cite as: Mater. Plast.
https://doi.org/10.37358/Mat.Plast.1964

OSIM Nr. R102356
ISSN Print 0025-5289
ISSN Online 2668-8220
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Materiale Plastice (Mater. Plast.), Year 2018, Volume 55, Issue 4, 502-506

https://doi.org/10.37358/MP.18.4.5062

Denise Bellisario, Fabrizio Quadrini, Gustavo Santolim1, Giovanni Matteo Tedde, Valerio Caputo, Paola Spitalieri, Federica Sangiuolo, Loredana Santo

Effects of Micro-Textured Polystyrene Substrates by Compression Molding on Cell Adhesion and Proliferation


Abstract:
Surface chemistry and micro-nanoscale topography of biomaterials can significantly influence tissue engineering and cell biology. In this study, polystyrene (PS) Petri dishes were subjected to microtexturing by compression molding process, which resulted in three-dimensional (3D) microscale surface topographies. Three different micropatterned surfaces were fabricated using bronze sintered molds with different mean pore pitch sizes. The surface changes and the morphological aspects were analyzed by 3D surface analyzer. The dishes were then used to investigate the cell behavior of Mouse Embryonic Fibroblasts (MEF) P4 cells. The surface micropatterning have affected in different ways the MEF cell adhesion and proliferation, related to the morphological changes in comparison with unmodified PS. At the increasing of the sintered particle dimensions of the mold, the cavities dimensions on the molded Petri increase and also the cells adhesion in the cavities seems to increase independently from the roughness inside them.


Keywords:
micro-textured surfaces; compression molding; polystyrene substrate; cell adhesion and proliferation

Issue: 2018 Volume 55, Issue 4
Pages: 502-506
Publication date: 2018/12/30
https://doi.org/10.37358/MP.18.4.5062
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
BELLISARIO, D., QUADRINI, F., SANTOLIM1, G., TEDDE, G.M., CAPUTO, V., SPITALIERI, P., SANGIUOLO, F., SANTO, L., Effects of Micro-Textured Polystyrene Substrates by Compression Molding on Cell Adhesion and Proliferation, Mater. Plast., 55(4), 2018, 502-506.

Vancouver
Bellisario D, Quadrini F, Santolim1 G, Tedde GM, Caputo V, Spitalieri P, Sangiuolo F, Santo L. Effects of Micro-Textured Polystyrene Substrates by Compression Molding on Cell Adhesion and Proliferation. Mater. Plast.[internet]. 2018 Dec;55(4):502-506. Available from: https://doi.org/10.37358/MP.18.4.5062


APA 6th edition
Bellisario, D., Quadrini, F., Santolim1, G., Tedde, G.M., Caputo, V., Spitalieri, P., Sangiuolo, F. & Santo, L. (2018). Effects of Micro-Textured Polystyrene Substrates by Compression Molding on Cell Adhesion and Proliferation. Materiale Plastice, 55(4), 502-506. https://doi.org/10.37358/MP.18.4.5062


Harvard
Bellisario, D., Quadrini, F., Santolim1, G., Tedde, G.M., Caputo, V., Spitalieri, P., Sangiuolo, F., Santo, L. (2018). 'Effects of Micro-Textured Polystyrene Substrates by Compression Molding on Cell Adhesion and Proliferation', Materiale Plastice, 55(4), pp. 502-506. https://doi.org/10.37358/MP.18.4.5062


IEEE
D. Bellisario, F. Quadrini, G. Santolim1, G.M. Tedde, V. Caputo, P. Spitalieri, F. Sangiuolo, L. Santo, "Effects of Micro-Textured Polystyrene Substrates by Compression Molding on Cell Adhesion and Proliferation". Materiale Plastice, vol. 55, no. 4, pp. 502-506, 2018. [online]. https://doi.org/10.37358/MP.18.4.5062


Text
Denise Bellisario, Fabrizio Quadrini, Gustavo Santolim1, Giovanni Matteo Tedde, Valerio Caputo, Paola Spitalieri, Federica Sangiuolo, Loredana Santo,
Effects of Micro-Textured Polystyrene Substrates by Compression Molding on Cell Adhesion and Proliferation,
Materiale Plastice,
Volume 55, Issue 4,
2018,
Pages 502-506,
ISSN 2668-8220,
https://doi.org/10.37358/MP.18.4.5062.
(https://revmaterialeplastice.ro/Articlegs.asp?ID=5062)
Keywords: micro-textured surfaces; compression molding; polystyrene substrate; cell adhesion and proliferation


RIS
TY - JOUR
T1 - Effects of Micro-Textured Polystyrene Substrates by Compression Molding on Cell Adhesion and Proliferation
A1 - Bellisario, Denise
A2 - Quadrini, Fabrizio
A3 - Santolim1, Gustavo
A4 - Tedde, Giovanni Matteo
A5 - Caputo, Valerio
A6 - Spitalieri, Paola
A7 - Sangiuolo, Federica
A8 - Santo, Loredana
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2018
VL - 55
IS - 4
SP - 502
EP - 506
UR - https://doi.org/10.37358/MP.18.4.5062
KW - micro-textured surfaces
KW - compression molding
KW - polystyrene substrate
KW - cell adhesion and proliferation
ER -


BibTex
@article{MatPlast2018P502,
author = {Bellisario Denise and Quadrini Fabrizio and Santolim1 Gustavo and Tedde Giovanni Matteo and Caputo Valerio and Spitalieri Paola and Sangiuolo Federica and Santo Loredana},
title = {Effects of Micro-Textured Polystyrene Substrates by Compression Molding on Cell Adhesion and Proliferation},
journal = {Materiale Plastice},
volume = {55},
number = {4},
pages = {502-506},
year = {2018},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.18.4.5062},
url = {https://revmaterialeplastice.ro/Articlegs.asp?ID=5062}
}
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