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Materiale Plastice
Cite as: Mater. Plast.
https://doi.org/10.37358/Mat.Plast.1964

OSIM Nr. R102356
ISSN Print 0025-5289
ISSN Online 2668-8220
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Materiale Plastice (Mater. Plast.), Year 2018, Volume 55, Issue 3, 291-294

https://doi.org/10.37358/MP.18.3.5015

Catalina Radulescu, Daniela Miricescu, Bogdan Calenic, Radu Radulescu, Iulia Stanescu, Anca Calenic, Alexandra Totan, Bogdana Virgolici, Daniela Balan, Maria Greabu

The Antioxidant Effect of PLGA Nanoparticles Encapsulated with Lutein in Rats Treated with Hypercaloric Diet


Abstract:
Poly lactic-co-glycolic acid (PLGA) is a biodegradable polymer that has been the focus of intense research due to its potential applications in medical research. Its uses in nanotechnology are underlined by its capability of targeting various cells and delivering active compounds to different human tissues. To date, PLGA nanoparticles are employed in areas such as vaccination therapy, diagnostic imaging procedure and various applications in various anticancer therapies. The aim of the present study is to measure and evaluate different correlations between oxidative stress parameters in spleen and liver following administration of nanoparticles encapsulated with lutein in an animal model. Our results show that acute oral administration of PLGA NPs induces a change in the oxidative stress status in both liver and spleen of rats, but does not induce oxidative stress damage to cell structures such as lipids or proteins.


Keywords:
polymeric nanoparticles; oxidative stress; liver; spleen; animal study

Issue: 2018 Volume 55, Issue 3
Pages: 291-294
Publication date: 2018/9/30
https://doi.org/10.37358/MP.18.3.5015
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
RADULESCU, C., MIRICESCU, D., CALENIC, B., RADULESCU, R., STANESCU, I., CALENIC, A., TOTAN, A., VIRGOLICI, B., BALAN, D., GREABU, M., The Antioxidant Effect of PLGA Nanoparticles Encapsulated with Lutein in Rats Treated with Hypercaloric Diet, Mater. Plast., 55(3), 2018, 291-294.

Vancouver
Radulescu C, Miricescu D, Calenic B, Radulescu R, Stanescu I, Calenic A, Totan A, Virgolici B, Balan D, Greabu M. The Antioxidant Effect of PLGA Nanoparticles Encapsulated with Lutein in Rats Treated with Hypercaloric Diet. Mater. Plast.[internet]. 2018 Jul;55(3):291-294. Available from: https://doi.org/10.37358/MP.18.3.5015


APA 6th edition
Radulescu, C., Miricescu, D., Calenic, B., Radulescu, R., Stanescu, I., Calenic, A.,... Greabu, M. (2018). The Antioxidant Effect of PLGA Nanoparticles Encapsulated with Lutein in Rats Treated with Hypercaloric Diet. Materiale Plastice, 55(3), 291-294. https://doi.org/10.37358/MP.18.3.5015


Harvard
Radulescu, C., Miricescu, D., Calenic, B., Radulescu, R., Stanescu, I., Calenic, A., Totan, A., Virgolici, B., Balan, D., Greabu, M. (2018). 'The Antioxidant Effect of PLGA Nanoparticles Encapsulated with Lutein in Rats Treated with Hypercaloric Diet', Materiale Plastice, 55(3), pp. 291-294. https://doi.org/10.37358/MP.18.3.5015


IEEE
C. Radulescu, D. Miricescu, B. Calenic, R. Radulescu, I. Stanescu, A. Calenic, A. Totan, B. Virgolici, D. Balan, M. Greabu, "The Antioxidant Effect of PLGA Nanoparticles Encapsulated with Lutein in Rats Treated with Hypercaloric Diet". Materiale Plastice, vol. 55, no. 3, pp. 291-294, 2018. [online]. https://doi.org/10.37358/MP.18.3.5015


Text
Catalina Radulescu, Daniela Miricescu, Bogdan Calenic, Radu Radulescu, Iulia Stanescu, Anca Calenic, Alexandra Totan, Bogdana Virgolici, Daniela Balan, Maria Greabu,
The Antioxidant Effect of PLGA Nanoparticles Encapsulated with Lutein in Rats Treated with Hypercaloric Diet,
Materiale Plastice,
Volume 55, Issue 3,
2018,
Pages 291-294,
ISSN 2668-8220,
https://doi.org/10.37358/MP.18.3.5015.
(https://revmaterialeplastice.ro/Articlegs.asp?ID=5015)
Keywords: polymeric nanoparticles; oxidative stress; liver; spleen; animal study


RIS
TY - JOUR
T1 - The Antioxidant Effect of PLGA Nanoparticles Encapsulated with Lutein in Rats Treated with Hypercaloric Diet
A1 - Radulescu, Catalina
A2 - Miricescu, Daniela
A3 - Calenic, Bogdan
A4 - Radulescu, Radu
A5 - Stanescu, Iulia
A6 - Calenic, Anca
A7 - Totan, Alexandra
A8 - Virgolici, Bogdana
A9 - Balan, Daniela
A10 - Greabu, Maria
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2018
VL - 55
IS - 3
SP - 291
EP - 294
UR - https://doi.org/10.37358/MP.18.3.5015
KW - polymeric nanoparticles
KW - oxidative stress
KW - liver
KW - spleen
KW - animal study
ER -


BibTex
@article{MatPlast2018P291,
author = {Radulescu Catalina and Miricescu Daniela and Calenic Bogdan and Radulescu Radu and Stanescu Iulia and Calenic Anca and Totan Alexandra and Virgolici Bogdana and Balan Daniela and Greabu Maria},
title = {The Antioxidant Effect of PLGA Nanoparticles Encapsulated with Lutein in Rats Treated with Hypercaloric Diet},
journal = {Materiale Plastice},
volume = {55},
number = {3},
pages = {291-294},
year = {2018},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.18.3.5015},
url = {https://revmaterialeplastice.ro/Articlegs.asp?ID=5015}
}
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