Synthesis and Comparative Characterization of Different Microparticles used as Biomaterials in Dentistry

Tofan, Sergiu Alexandru; Olteanu, Cristian; Szuhanek, Camelia; Popovici, Ramona Amina; Luca, Magda Mihaela; Iftode, Andrada; Pavel, Ioana Zinuca; Bonta, Dan Florin

Sergiu Alexandru Tofan, Cristian Olteanu, Camelia Szuhanek, Ramona Amina Popovici, Magda Mihaela Luca, Andrada Iftode, Ioana Zinuca Pavel, Dan Florin Bonta

Synthesis and Comparative Characterization of Different Microparticles used as Biomaterials in Dentistry

Abstract:
A biomaterial must be biologically compatible, mechanical, functional, corrosion resistant and easily adapt to clinical and laboratory technologies. Dental biomaterials are materials used to replace a part of a living system or to work closely with living tissue. Many scientific articles present different polymeric biocomposites with possible application in dentistry and this is a proof of the opportunity of a research in a field in full ascent and with great availability in the promotion of materials destined to “work under biological constraint” and which must also meet the functional requirements of a dental implant. The objectives of this research were to obtain and to comparatively evaluate different polymeric microparticles that can be used in dentistry. The samples based on poly(lactic-co-glycolic acid) and respectively polyurethane microparticles were characterized by pH and Zetasizer measurements, and in vitro cytotoxicity assays. The results indicate the obtaining of particles with a neutral pH, medium homogeneity, and with different tendencies to form agglomerations. Their low cytotoxicity, tested on the primary human gingival fibroblasts by MTT and LDH techniques, indicates that these microparticles are safe to be tested in further clinical evaluations.

Keywords:
PLGA; polyurethane; Zetasizer; HGF primary gingival fibroblast; cytotoxicity

Issue: 2021 Volume 58, Issue 2

Pages: 192-200

Publication date: 2021/7/5

https://doi.org/10.37358/MP.21.2.5491

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
TOFAN, S.A., OLTEANU, C., SZUHANEK, C., POPOVICI, R.A., LUCA, M.M., IFTODE, A., PAVEL, I.Z., BONTA, D.F., Synthesis and Comparative Characterization of Different Microparticles used as Biomaterials in Dentistry, Mater. Plast., 58(2), 2021, 192-200. https://doi.org/10.37358/MP.21.2.5491

Vancouver
Tofan SA, Olteanu C, Szuhanek C, Popovici RA, Luca MM, Iftode A, Pavel IZ, Bonta DF. Synthesis and Comparative Characterization of Different Microparticles used as Biomaterials in Dentistry. Mater. Plast.[internet]. 2021 Apr;58(2):192-200. Available from: https://doi.org/10.37358/MP.21.2.5491

APA 6th edition
Tofan, S.A., Olteanu, C., Szuhanek, C., Popovici, R.A., Luca, M.M., Iftode, A., Pavel, I.Z. & Bonta, D.F. (2021). Synthesis and Comparative Characterization of Different Microparticles used as Biomaterials in Dentistry. Materiale Plastice, 58(2), 192-200. https://doi.org/10.37358/MP.21.2.5491

Harvard
Tofan, S.A., Olteanu, C., Szuhanek, C., Popovici, R.A., Luca, M.M., Iftode, A., Pavel, I.Z., Bonta, D.F. (2021). 'Synthesis and Comparative Characterization of Different Microparticles used as Biomaterials in Dentistry', Materiale Plastice, 58(2), pp. 192-200. https://doi.org/10.37358/MP.21.2.5491

IEEE
S.A. Tofan, C. Olteanu, C. Szuhanek, R.A. Popovici, M.M. Luca, A. Iftode, I.Z. Pavel, D.F. Bonta, "Synthesis and Comparative Characterization of Different Microparticles used as Biomaterials in Dentistry". Materiale Plastice, vol. 58, no. 2, pp. 192-200, 2021. [online]. https://doi.org/10.37358/MP.21.2.5491

Text
Sergiu Alexandru Tofan, Cristian Olteanu, Camelia Szuhanek, Ramona Amina Popovici, Magda Mihaela Luca, Andrada Iftode, Ioana Zinuca Pavel, Dan Florin Bonta,
Synthesis and Comparative Characterization of Different Microparticles used as Biomaterials in Dentistry,
Materiale Plastice,
Volume 58, Issue 2,
2021,
Pages 192-200,
ISSN 2668-8220,
https://doi.org/10.37358/MP.21.2.5491.
(https://revmaterialeplastice.ro/Articles.asp?ID=5491)
Keywords: PLGA; polyurethane; Zetasizer; HGF primary gingival fibroblast; cytotoxicity

RIS
TY - JOUR
T1 - Synthesis and Comparative Characterization of Different Microparticles used as Biomaterials in Dentistry
A1 - Tofan, Sergiu Alexandru
A2 - Olteanu, Cristian
A3 - Szuhanek, Camelia
A4 - Popovici, Ramona Amina
A5 - Luca, Magda Mihaela
A6 - Iftode, Andrada
A7 - Pavel, Ioana Zinuca
A8 - Bonta, Dan Florin
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2021
VL - 58
IS - 2
SP - 192
EP - 200
UR - https://doi.org/10.37358/MP.21.2.5491
KW - PLGA
KW - polyurethane
KW - Zetasizer
KW - HGF primary gingival fibroblast
KW - cytotoxicity
ER -

BibTex
@article{MatPlast2021P192,
author = {Tofan Sergiu Alexandru and Olteanu Cristian and Szuhanek Camelia and Popovici Ramona Amina and Luca Magda Mihaela and Iftode Andrada and Pavel Ioana Zinuca and Bonta Dan Florin},
title = {Synthesis and Comparative Characterization of Different Microparticles used as Biomaterials in Dentistry},
journal = {Materiale Plastice},
volume = {58},
number = {2},
pages = {192-200},
year = {2021},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.21.2.5491},
url = {https://revmaterialeplastice.ro/Articles.asp?ID=5491}
}

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