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Materiale Plastice
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https://doi.org/10.37358/Mat.Plast.1964

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Materiale Plastice (Mater. Plast.), Year 2020, Volume 57, Issue 2, 191-198

https://doi.org/10.37358/MP.20.2.5365

George Roiu, Simona Cavalu, Alin Teusdea, Denisa A. Petricas-Heredea, Ovidiu Fratila

Assessment of Antibiotic Influence on Structural Modifications of Amniotic Membrane by FTIR Spectroscopy


Abstract:
The amniotic membrane is a readily available biomaterial with an important potential for tissue regeneration in dermatology and ophtalmology, with anti-inflammatory and anti-microbial properties. The extracellular matrix of the amniotic membrane is composed mainly of collagen, fibronectin and laminin. The purpose of our study was to investigate the structural modifications of collagen extracellular matrix of amniotic membrane upon interaction with two different antibiotics, frequently used in surgical and post- surgical procedure, respectively ciprofloxacin and gentamicin. SEM micrographs evidenced the ultrastructure features of dried amniotic membrane, with laminar structure, flexible, transparent, with no blood vesels or nerves. FTIR spectroscopy combined with deconvolution techniques was applied with the aim to determine the extent of denaturation upon treatment with different antibiotics. By spectral analysis, we concluded that gentamicin treatment is more favorable compared to ciprofloxacin, as the denaturation process is reflected by the lower sheet/turns ratio of the secondary structure composition.


Keywords:
amniotic membrane; natural polymer; FTIR spectroscopy; protein secondary structure

Issue: 2020 Volume 57, Issue 2
Pages: 191-198
Publication date: 2019/7/1
https://doi.org/10.37358/MP.20.2.5365
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
ROIU, G., CAVALU, S., TEUSDEA, A., PETRICAS-HEREDEA, D.A., FRATILA, O., Assessment of Antibiotic Influence on Structural Modifications of Amniotic Membrane by FTIR Spectroscopy, Mater. Plast., 57(2), 2020, 191-198. https://doi.org/10.37358/MP.20.2.5365

Vancouver
Roiu G, Cavalu S, Teusdea A, Petricas-Heredea DA, Fratila O. Assessment of Antibiotic Influence on Structural Modifications of Amniotic Membrane by FTIR Spectroscopy. Mater. Plast.[internet]. 2020 Apr;57(2):191-198. Available from: https://doi.org/10.37358/MP.20.2.5365


APA 6th edition
Roiu, G., Cavalu, S., Teusdea, A., Petricas-Heredea, D.A. & Fratila, O. (2020). Assessment of Antibiotic Influence on Structural Modifications of Amniotic Membrane by FTIR Spectroscopy. Materiale Plastice, 57(2), 191-198. https://doi.org/10.37358/MP.20.2.5365


Harvard
Roiu, G., Cavalu, S., Teusdea, A., Petricas-Heredea, D.A., Fratila, O. (2020). 'Assessment of Antibiotic Influence on Structural Modifications of Amniotic Membrane by FTIR Spectroscopy', Materiale Plastice, 57(2), pp. 191-198. https://doi.org/10.37358/MP.20.2.5365


IEEE
G. Roiu, S. Cavalu, A. Teusdea, D.A. Petricas-Heredea, O. Fratila, "Assessment of Antibiotic Influence on Structural Modifications of Amniotic Membrane by FTIR Spectroscopy". Materiale Plastice, vol. 57, no. 2, pp. 191-198, 2020. [online]. https://doi.org/10.37358/MP.20.2.5365


Text
George Roiu, Simona Cavalu, Alin Teusdea, Denisa A. Petricas-Heredea, Ovidiu Fratila,
Assessment of Antibiotic Influence on Structural Modifications of Amniotic Membrane by FTIR Spectroscopy,
Materiale Plastice,
Volume 57, Issue 2,
2020,
Pages 191-198,
ISSN 2668-8220,
https://doi.org/10.37358/MP.20.2.5365.
(https://revmaterialeplastice.ro/Articles.asp?ID=5365)
Keywords: amniotic membrane; natural polymer; FTIR spectroscopy; protein secondary structure


RIS
TY - JOUR
T1 - Assessment of Antibiotic Influence on Structural Modifications of Amniotic Membrane by FTIR Spectroscopy
A1 - Roiu, George
A2 - Cavalu, Simona
A3 - Teusdea, Alin
A4 - Petricas-Heredea, Denisa A.
A5 - Fratila, Ovidiu
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2020
VL - 57
IS - 2
SP - 191
EP - 198
UR - https://doi.org/10.37358/MP.20.2.5365
KW - amniotic membrane
KW - natural polymer
KW - FTIR spectroscopy
KW - protein secondary structure
ER -


BibTex
@article{MatPlast2020P191,
author = {Roiu George and Cavalu Simona and Teusdea Alin and Petricas-Heredea Denisa A. and Fratila Ovidiu},
title = {Assessment of Antibiotic Influence on Structural Modifications of Amniotic Membrane by FTIR Spectroscopy},
journal = {Materiale Plastice},
volume = {57},
number = {2},
pages = {191-198},
year = {2020},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.20.2.5365},
url = {https://revmaterialeplastice.ro/Articles.asp?ID=5365}
}


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