Accelerating the Bone Healing Process by the Intervention of the Platelet Growth Factors Impregnated in Collagen. An experimental and theoretical mathematical model

Susanu, Sidonia; Popescu, Mara; Caba, Bogdan; Plamadeala, Petru; Moraru, Andreea; Costin, Dan; Gavrilut, Gabriel; Agop, Maricel; Cioca, Gabriela

Sidonia Susanu, Mara Popescu, Bogdan Caba, Petru Plamadeala, Andreea Moraru, Dan Costin, Gabriel Gavrilut, Maricel Agop, Gabriela Cioca

Accelerating the Bone Healing Process by the Intervention of the Platelet Growth Factors Impregnated in Collagen. An experimental and theoretical mathematical model

Abstract:
A bone defect with standard dimensions and localization is produced. Inside this defect a polymer (collagen sponge) impregnated with growing factors, i. e. bone morphogenetic protein - BMP, is introduced. For the witness lot, the same defect is produced, in which the same polymer is introduced, but without any growing factors. It is found that the growing factor not only remains at the initial site, but also has effect on the bone regeneration process. A mathematical model is constructed using a field theory of multifractal type based on the spontaneous symmetry breaking mechanism to exploit such dynamics in biostructures. This mechanism contains all the informational “ingredients”: the multivalent logic based multifractal bit, the algorithm based networks through spatial cnoidal modes of oscilation, etc. In such context, the evolution of all biostructures, through a mechanism that mimics a 3D biological printer, can become operational.

Keywords:
bone; collagen; multifractal

Issue: 2019 Volume 56, Issue 4

Pages: 973-979

Publication date: 2019/12/30

https://doi.org/10.37358/MP.19.4.5294

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This article is published under the Creative Commons Attribution 4.0 International License

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Cite this article as:
SUSANU, S., POPESCU, M., CABA, B., PLAMADEALA, P., MORARU, A., COSTIN, D., GAVRILUT, G., AGOP, M., CIOCA, G., Accelerating the Bone Healing Process by the Intervention of the Platelet Growth Factors Impregnated in Collagen. An experimental and theoretical mathematical model, Mater. Plast., 56(4), 2019, 973-979. https://doi.org/10.37358/MP.19.4.5294

Vancouver
Susanu S, Popescu M, Caba B, Plamadeala P, Moraru A, Costin D, Gavrilut G, Agop M, Cioca G. Accelerating the Bone Healing Process by the Intervention of the Platelet Growth Factors Impregnated in Collagen. An experimental and theoretical mathematical model. Mater. Plast.[internet]. 2019 Dec;56(4):973-979. Available from: https://doi.org/10.37358/MP.19.4.5294

APA 6th edition
Susanu, S., Popescu, M., Caba, B., Plamadeala, P., Moraru, A., Costin, D.,... Cioca, G. (2019). Accelerating the Bone Healing Process by the Intervention of the Platelet Growth Factors Impregnated in Collagen. An experimental and theoretical mathematical model. Materiale Plastice, 56(4), 973-979. https://doi.org/10.37358/MP.19.4.5294

Harvard
Susanu, S., Popescu, M., Caba, B., Plamadeala, P., Moraru, A., Costin, D., Gavrilut, G., Agop, M., Cioca, G. (2019). 'Accelerating the Bone Healing Process by the Intervention of the Platelet Growth Factors Impregnated in Collagen. An experimental and theoretical mathematical model', Materiale Plastice, 56(4), pp. 973-979. https://doi.org/10.37358/MP.19.4.5294

IEEE
S. Susanu, M. Popescu, B. Caba, P. Plamadeala, A. Moraru, D. Costin, G. Gavrilut, M. Agop, G. Cioca, "Accelerating the Bone Healing Process by the Intervention of the Platelet Growth Factors Impregnated in Collagen. An experimental and theoretical mathematical model". Materiale Plastice, vol. 56, no. 4, pp. 973-979, 2019. [online]. https://doi.org/10.37358/MP.19.4.5294

Text
Sidonia Susanu, Mara Popescu, Bogdan Caba, Petru Plamadeala, Andreea Moraru, Dan Costin, Gabriel Gavrilut, Maricel Agop, Gabriela Cioca,
Accelerating the Bone Healing Process by the Intervention of the Platelet Growth Factors Impregnated in Collagen. An experimental and theoretical mathematical model,
Materiale Plastice,
Volume 56, Issue 4,
2019,
Pages 973-979,
ISSN 2668-8220,
https://doi.org/10.37358/MP.19.4.5294.
(https://revmaterialeplastice.ro/Articles.asp?ID=5294)
Keywords: bone; collagen; multifractal

RIS
TY - JOUR
T1 - Accelerating the Bone Healing Process by the Intervention of the Platelet Growth Factors Impregnated in Collagen. An experimental and theoretical mathematical model
A1 - Susanu, Sidonia
A2 - Popescu, Mara
A3 - Caba, Bogdan
A4 - Plamadeala, Petru
A5 - Moraru, Andreea
A6 - Costin, Dan
A7 - Gavrilut, Gabriel
A8 - Agop, Maricel
A9 - Cioca, Gabriela
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2019
VL - 56
IS - 4
SP - 973
EP - 979
UR - https://doi.org/10.37358/MP.19.4.5294
KW - bone
KW - collagen
KW - multifractal
ER -

BibTex
@article{MatPlast2019P973,
author = {Susanu Sidonia and Popescu Mara and Caba Bogdan and Plamadeala Petru and Moraru Andreea and Costin Dan and Gavrilut Gabriel and Agop Maricel and Cioca Gabriela},
title = {Accelerating the Bone Healing Process by the Intervention of the Platelet Growth Factors Impregnated in Collagen. An experimental and theoretical mathematical model},
journal = {Materiale Plastice},
volume = {56},
number = {4},
pages = {973-979},
year = {2019},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.19.4.5294},
url = {https://revmaterialeplastice.ro/Articles.asp?ID=5294}
}

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