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Materiale Plastice
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https://doi.org/10.37358/Mat.Plast.1964

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ISSN Print 0025-5289
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Materiale Plastice (Mater. Plast.), Year 2019, Volume 56, Issue 1, 291-294

https://doi.org/10.37358/MP.19.1.5168

Crinela Utescu, Delia Berceanu-Vaduva, Constantin Tudor Luca, Claudia Farcas, Victor Dumitrascu, Matilda Radulescu

Preliminary in vitro Evaluation of a Semisynthetic Oestrogen Polymer-based Formulation


Abstract:
Oestrogen hormones play key roles in the human body, are involved in complex mechanisms, both beneficial and unwanted. Because semisynthetic oestrogens are commonly used today in various hormonal therapies, they has inevitably been linked to the appearance of certain carcinogenic processes, which are primarily based on oestrogen-based drugs, either as initiators or promoters. A promising alternative that can help reduce unwanted effects is to capture the active substance in a polymeric matrix that is capable of retaining its biological activity. In this study, activity on the viability of breast cancer cells with expressed oestrogen receptors of a polymeric formulation with ethinylestradiol and polylactic acid was evaluated.


Keywords:
semisynthetic oestrogen; polymer particles; breast cancer; cell

Issue: 2019 Volume 56, Issue 1
Pages: 291-294
Publication date: 30/03/2019
https://doi.org/10.37358/MP.19.1.5168
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
UTESCU, C., BERCEANU-VADUVA, D., LUCA, C.T., FARCAS, C., DUMITRASCU, V., RADULESCU, M., Preliminary in vitro Evaluation of a Semisynthetic Oestrogen Polymer-based Formulation, Mater. Plast., 56(1), 2019, 291-294.

Vancouver
Utescu C, Berceanu-Vaduva D, Luca CT, Farcas C, Dumitrascu V, Radulescu M. Preliminary in vitro Evaluation of a Semisynthetic Oestrogen Polymer-based Formulation. Mater. Plast.[internet]. 2019 Jan;56(1):291-294. Available from: https://doi.org/10.37358/MP.19.1.5168


APA 6th edition
Utescu, C., Berceanu-Vaduva, D., Luca, C.T., Farcas, C., Dumitrascu, V. & Radulescu, M. (2019). Preliminary in vitro Evaluation of a Semisynthetic Oestrogen Polymer-based Formulation. Materiale Plastice, 56(1), 291-294. https://doi.org/10.37358/MP.19.1.5168


Harvard
Utescu, C., Berceanu-Vaduva, D., Luca, C.T., Farcas, C., Dumitrascu, V., Radulescu, M. (2019). 'Preliminary in vitro Evaluation of a Semisynthetic Oestrogen Polymer-based Formulation', Materiale Plastice, 56(1), pp. 291-294. https://doi.org/10.37358/MP.19.1.5168


IEEE
C. Utescu, D. Berceanu-Vaduva, C.T. Luca, C. Farcas, V. Dumitrascu, M. Radulescu, "Preliminary in vitro Evaluation of a Semisynthetic Oestrogen Polymer-based Formulation". Materiale Plastice, vol. 56, no. 1, pp. 291-294, 2019. [online]. https://doi.org/10.37358/MP.19.1.5168


Text
Crinela Utescu, Delia Berceanu-Vaduva, Constantin Tudor Luca, Claudia Farcas, Victor Dumitrascu, Matilda Radulescu,
Preliminary in vitro Evaluation of a Semisynthetic Oestrogen Polymer-based Formulation,
Materiale Plastice,
Volume 56, Issue 1,
2019,
Pages 291-294,
ISSN 2668-8220,
https://doi.org/10.37358/MP.19.1.5168.
(https://revmaterialeplastice.ro/Articles.asp?ID=5168)
Keywords: semisynthetic oestrogen; polymer particles; breast cancer; cell


RIS
TY - JOUR
T1 - Preliminary in vitro Evaluation of a Semisynthetic Oestrogen Polymer-based Formulation
A1 - Utescu, Crinela
A2 - Berceanu-Vaduva, Delia
A3 - Luca, Constantin Tudor
A4 - Farcas, Claudia
A5 - Dumitrascu, Victor
A6 - Radulescu, Matilda
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2019
VL - 56
IS - 1
SP - 291
EP - 294
UR - https://doi.org/10.37358/MP.19.1.5168
KW - semisynthetic oestrogen
KW - polymer particles
KW - breast cancer
KW - cell
ER -


BibTex
@article{MatPlast2019P291,
author = {Utescu Crinela and Berceanu-Vaduva Delia and Luca Constantin Tudor and Farcas Claudia and Dumitrascu Victor and Radulescu Matilda},
title = {Preliminary in vitro Evaluation of a Semisynthetic Oestrogen Polymer-based Formulation},
journal = {Materiale Plastice},
volume = {56},
number = {1},
pages = {291-294},
year = {2019},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.19.1.5168},
url = {https://revmaterialeplastice.ro/Articles.asp?ID=5168}
}

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