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Materiale Plastice
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https://doi.org/10.37358/Mat.Plast.1964

OSIM Nr. R102356
ISSN Print 0025-5289
ISSN Online 2668-8220
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Materiale Plastice (Mater. Plast.), Year 2019, Volume 56, Issue 1, 148-155

https://doi.org/10.37358/MP.19.1.5141

Rodica Sirbu, Alef Mustafa, Aneta Tomescu, Gabriela Stanciu, Emin Cadar

Rheological and Microbiological Study on Bio-Composites with Marine Chitosan Polymers from Black Sea Stone Crabs used in Medical Therapy of Tissue Regeneration


Abstract:
In the last years, health care professionals faced with an increasing number of patients suffering from wounds, burns and bedsores difficult to treat and heal. During the wound healing process, the dressing protects the injured area and contributes to the recovery of dermal and epidermal tissues. Because their biocompatibility, biodegradability and similarity to macromolecules recognized by the human body, some natural polymers such as polysaccharides (alginates, chitin, chitosan), proteoglycans and proteins (collagen, gelatin, fibrin) are extensively are used in wounds and burns management. The study presents a research of new semi-solid formulations of bio-composites based on chitosan extracted from the stone crab Pachygrapsus Mormoratus found on the Black Sea shores. The bio-composites were obtained from natural polymeric compounds, Chitosan (CT), hyaluronic acid (HA) and lanolin(L), to which silver sulfadiazine (S), was added. Several semi-solid formulations have been performed for which the antimicrobial activity on gram-positive and gram-negative germ cultures and the rheological behavior was studied. The bio-composites that were obtained provide an optimal micro-environment for cell proliferation, migration and differentiation, due to their biocompatibility, biodegradability, peculiar structure and good antimicrobial activity.


Keywords:
chitosan; hyaluronic acid; rheological behavior; antimicrobial activity

Issue: 2019 Volume 56, Issue 1
Pages: 148-155
Publication date: 2019/3/30
https://doi.org/10.37358/MP.19.1.5141
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Creative Commons License
This article is published under the Creative Commons Attribution 4.0 International License
Citation Styles
Cite this article as:
SIRBU, R., MUSTAFA, A., TOMESCU, A., STANCIU, G., CADAR, E., Rheological and Microbiological Study on Bio-Composites with Marine Chitosan Polymers from Black Sea Stone Crabs used in Medical Therapy of Tissue Regeneration, Mater. Plast., 56(1), 2019, 148-155.

Vancouver
Sirbu R, Mustafa A, Tomescu A, Stanciu G, Cadar E. Rheological and Microbiological Study on Bio-Composites with Marine Chitosan Polymers from Black Sea Stone Crabs used in Medical Therapy of Tissue Regeneration. Mater. Plast.[internet]. 2019 Jan;56(1):148-155. Available from: https://doi.org/10.37358/MP.19.1.5141


APA 6th edition
Sirbu, R., Mustafa, A., Tomescu, A., Stanciu, G. & Cadar, E. (2019). Rheological and Microbiological Study on Bio-Composites with Marine Chitosan Polymers from Black Sea Stone Crabs used in Medical Therapy of Tissue Regeneration. Materiale Plastice, 56(1), 148-155. https://doi.org/10.37358/MP.19.1.5141


Harvard
Sirbu, R., Mustafa, A., Tomescu, A., Stanciu, G., Cadar, E. (2019). 'Rheological and Microbiological Study on Bio-Composites with Marine Chitosan Polymers from Black Sea Stone Crabs used in Medical Therapy of Tissue Regeneration', Materiale Plastice, 56(1), pp. 148-155. https://doi.org/10.37358/MP.19.1.5141


IEEE
R. Sirbu, A. Mustafa, A. Tomescu, G. Stanciu, E. Cadar, "Rheological and Microbiological Study on Bio-Composites with Marine Chitosan Polymers from Black Sea Stone Crabs used in Medical Therapy of Tissue Regeneration". Materiale Plastice, vol. 56, no. 1, pp. 148-155, 2019. [online]. https://doi.org/10.37358/MP.19.1.5141


Text
Rodica Sirbu, Alef Mustafa, Aneta Tomescu, Gabriela Stanciu, Emin Cadar,
Rheological and Microbiological Study on Bio-Composites with Marine Chitosan Polymers from Black Sea Stone Crabs used in Medical Therapy of Tissue Regeneration,
Materiale Plastice,
Volume 56, Issue 1,
2019,
Pages 148-155,
ISSN 2668-8220,
https://doi.org/10.37358/MP.19.1.5141.
(https://revmaterialeplastice.ro/Articlegs.asp?ID=5141)
Keywords: chitosan; hyaluronic acid; rheological behavior; antimicrobial activity


RIS
TY - JOUR
T1 - Rheological and Microbiological Study on Bio-Composites with Marine Chitosan Polymers from Black Sea Stone Crabs used in Medical Therapy of Tissue Regeneration
A1 - Sirbu, Rodica
A2 - Mustafa, Alef
A3 - Tomescu, Aneta
A4 - Stanciu, Gabriela
A5 - Cadar, Emin
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2019
VL - 56
IS - 1
SP - 148
EP - 155
UR - https://doi.org/10.37358/MP.19.1.5141
KW - chitosan
KW - hyaluronic acid
KW - rheological behavior
KW - antimicrobial activity
ER -


BibTex
@article{MatPlast2019P148,
author = {Sirbu Rodica and Mustafa Alef and Tomescu Aneta and Stanciu Gabriela and Cadar Emin},
title = {Rheological and Microbiological Study on Bio-Composites with Marine Chitosan Polymers from Black Sea Stone Crabs used in Medical Therapy of Tissue Regeneration},
journal = {Materiale Plastice},
volume = {56},
number = {1},
pages = {148-155},
year = {2019},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.19.1.5141},
url = {https://revmaterialeplastice.ro/Articlegs.asp?ID=5141}
}
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