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Materiale Plastice (Mater. Plast.), Year 2016, Volume 53, Issue 2, 321-325



Cristian Martu, Madalina Gabriela Georgescu, Ioana Martu, Corina Butnaru, Vlad Porumb, Luminita Radulescu

Utility of Drug Loaded Nanoparticles in the Treatment of Inner Ear Pathology


Abstract:
The lack of drug specificity for inner ear structures and the side effects of systemic administration have determined the treatment strategies to evolve from systemic administration to local application of drugs. The disadvantages of systemic or local administration of drugs for the inner ear, have led to the development of nanoparticles with specific activity. The study presents current research advances regarding the use of nanoparticles (liposomes, PLGA, dendrimers, silica or magnetic nanoparticles, etc.) in inner ear pathology treatment.


Keywords:
nanoparticle; inner ear; deafness; drug administration

Issue: 2016 Volume 53, Issue 2
Pages: 321-325
Publication date: 2016/6/30
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