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Materiale Plastice
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https://doi.org/10.37358/Mat.Plast.1964

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Materiale Plastice (Mater. Plast.), Year 2015, Volume 52, Issue 3,





Maria Rapa, Catalin Zaharia, Maria Lungu, Paul Octavian Stanescu, Petruta Stoica, Elena Grosu, Rodica Tatia, Viorica Coroiu Biocompatibility of PHAs Biocomposites Obtained by Melt Processing


Abstract:
The present work reports on the biocompatibility of poly (3-hydroxybutyrate) and poly (3-hydroxybutyrate-co-3-hydroxyvalerate) loaded with bacterial cellulose and microcrystalline cellulose via melt processing. Biocompatibility was tested by physico-chemical and in vitro methods. Physico-chemical tests of biocomposites, such as reducing substances, acidity, alkalinity, absorbance by UV/VIS, residue on evaporation were performed on aqueous extract. The cell viability was evaluated by MTT assay. Cell morphology evaluation of cell culture treated with composites was visualized by light microscopy. Also, thermal properties of biocomposites were investigated by DSC analysis. The obtained results have shown good biocompatibility of all biocomposites. Keywords: biocompatibility, physico-chemical tests, cytotoxicity, melt processing



Issue: 2015 Volume 52, Issue 3
Pages:
Publication date: 2015/9/30
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