Comparative Characterization of Birch Bark Extracts Encapsulated Inside Polyurethane Microstructures

Borcan, Florin; Preda, Marius; Borcan, Livia Cristina; Pinzaru, Iulia; Florescu, Sorin; Sisu, Eugen; Poenaru, Marioara

Florin Borcan, Marius Preda, Livia Cristina Borcan, Iulia Pinzaru, Sorin Florescu, Eugen Sisu, Marioara Poenaru

Comparative Characterization of Birch Bark Extracts Encapsulated Inside Polyurethane Microstructures

Abstract:
The phytotherapy is based on the consume of fruits, vegetables and medicinal plants; they contain mixtures of bioactive chemical substances (carotenoids, phenolic acids, flavonoids, coumarins, tannins, organosulfur compounds) with synergic effects on the treatment of diseases. Nano- and micro-carriers are very useful drug delivery systems which can improve the transmembrane transfer of natural extracts. In the present study, betulin and two birch bark extracts were encapsulated inside polyurethane microstructures. Structures’ size, homogeneity and surface charge were studied using a Zetasizer, while DSC analysis was involved to assay structures’ thermal behavior. Irritation effects were monitored by non-invasive techniques on human skin. The results indicate the obtaining of structures with size around 200-250 nm, with a positive surface charge and a very good thermal stability. The non-irritation potential recommends these structures as a safe delivery system used for natural extracts.

Keywords:
betulin; drug carrier; erythema; polymer; TEWA; Zeta potential

Issue: 2018 Volume 55, Issue 3

Pages: 385-388

Publication date: 2018/9/30

https://doi.org/10.37358/MP.18.3.5035

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
BORCAN, F., PREDA, M., BORCAN, L.C., PINZARU, I., FLORESCU, S., SISU, E., POENARU, M., Comparative Characterization of Birch Bark Extracts Encapsulated Inside Polyurethane Microstructures, Mater. Plast., 55(3), 2018, 385-388. https://doi.org/10.37358/MP.18.3.5035

Vancouver
Borcan F, Preda M, Borcan LC, Pinzaru I, Florescu S, Sisu E, Poenaru M. Comparative Characterization of Birch Bark Extracts Encapsulated Inside Polyurethane Microstructures. Mater. Plast.[internet]. 2018 Jul;55(3):385-388. Available from: https://doi.org/10.37358/MP.18.3.5035

APA 6th edition
Borcan, F., Preda, M., Borcan, L.C., Pinzaru, I., Florescu, S., Sisu, E. & Poenaru, M. (2018). Comparative Characterization of Birch Bark Extracts Encapsulated Inside Polyurethane Microstructures. Materiale Plastice, 55(3), 385-388. https://doi.org/10.37358/MP.18.3.5035

Harvard
Borcan, F., Preda, M., Borcan, L.C., Pinzaru, I., Florescu, S., Sisu, E., Poenaru, M. (2018). 'Comparative Characterization of Birch Bark Extracts Encapsulated Inside Polyurethane Microstructures', Materiale Plastice, 55(3), pp. 385-388. https://doi.org/10.37358/MP.18.3.5035

IEEE
F. Borcan, M. Preda, L.C. Borcan, I. Pinzaru, S. Florescu, E. Sisu, M. Poenaru, "Comparative Characterization of Birch Bark Extracts Encapsulated Inside Polyurethane Microstructures". Materiale Plastice, vol. 55, no. 3, pp. 385-388, 2018. [online]. https://doi.org/10.37358/MP.18.3.5035

Text
Florin Borcan, Marius Preda, Livia Cristina Borcan, Iulia Pinzaru, Sorin Florescu, Eugen Sisu, Marioara Poenaru,
Comparative Characterization of Birch Bark Extracts Encapsulated Inside Polyurethane Microstructures,
Materiale Plastice,
Volume 55, Issue 3,
2018,
Pages 385-388,
ISSN 2668-8220,
https://doi.org/10.37358/MP.18.3.5035.
(https://revmaterialeplastice.ro/Articles.asp?ID=5035)
Keywords: betulin; drug carrier; erythema; polymer; TEWA; Zeta potential

RIS
TY - JOUR
T1 - Comparative Characterization of Birch Bark Extracts Encapsulated Inside Polyurethane Microstructures
A1 - Borcan, Florin
A2 - Preda, Marius
A3 - Borcan, Livia Cristina
A4 - Pinzaru, Iulia
A5 - Florescu, Sorin
A6 - Sisu, Eugen
A7 - Poenaru, Marioara
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2018
VL - 55
IS - 3
SP - 385
EP - 388
UR - https://doi.org/10.37358/MP.18.3.5035
KW - betulin
KW - drug carrier
KW - erythema
KW - polymer
KW - TEWA
KW - Zeta potential
ER -

BibTex
@article{MatPlast2018P385,
author = {Borcan Florin and Preda Marius and Borcan Livia Cristina and Pinzaru Iulia and Florescu Sorin and Sisu Eugen and Poenaru Marioara},
title = {Comparative Characterization of Birch Bark Extracts Encapsulated Inside Polyurethane Microstructures},
journal = {Materiale Plastice},
volume = {55},
number = {3},
pages = {385-388},
year = {2018},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.18.3.5035},
url = {https://revmaterialeplastice.ro/Articles.asp?ID=5035}
}

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