Mechanical Behaviour of Orthopaedic Cement Loaded with Antibiotics in the Operation Room

Fleaca, Radu; Mitariu, Sebastian Ioan Cernusca; Oleksik, Valentin; Oleksik, Mihaela; Roman, Mihai

Radu Fleaca, Sebastian Ioan Cernusca Mitariu, Valentin Oleksik, Mihaela Oleksik, Mihai Roman

Mechanical Behaviour of Orthopaedic Cement Loaded with Antibiotics in the Operation Room

Abstract:
Using antibiotic impregnated cement is an important mean to treat and prevent periprostetic joint infections. This complication requires for treatment important financial and technical resources. Adding antibiotics to orthopaedic cement may alter its mechanical properties with possible reduced time of prosthesis survival rate. This study analyze the mechanical properties of cement mixed with antibiotics in the operation room, which helps reducing costs and permit a more specific antibiotic local therapy. All tested antibiotics used in this study does not change the mechanical behavior of the orthopaedic cement when mixed in therapeutic doses, all alterations seems to be at a level below clinical significance. Mixing antibiotics in Orthopedic cement leads to minor decrease of the mechanical properties for cefazolin, cefuroxime, ceftazidime, meropenem and vancomycin and a mechanical significant decrease for gentamicin and clindamycin.

Keywords:
orthopaedic cement; polymethylmethacrylate; antibiotic; mechanical properties; periprostetic joint infection

Issue: 2017 Volume 54, Issue 2

Pages: 402-407

Publication date: 2017/6/30

https://doi.org/10.37358/MP.17.2.4860

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
FLEACA, R., MITARIU, S.I.C., OLEKSIK, V., OLEKSIK, M., ROMAN, M., Mechanical Behaviour of Orthopaedic Cement Loaded with Antibiotics in the Operation Room, Mater. Plast., 54(2), 2017, 402-407. https://doi.org/10.37358/MP.17.2.4860

Vancouver
Fleaca R, Mitariu SIC, Oleksik V, Oleksik M, Roman M. Mechanical Behaviour of Orthopaedic Cement Loaded with Antibiotics in the Operation Room. Mater. Plast.[internet]. 2017 Apr;54(2):402-407. Available from: https://doi.org/10.37358/MP.17.2.4860

APA 6th edition
Fleaca, R., Mitariu, S.I.C., Oleksik, V., Oleksik, M. & Roman, M. (2017). Mechanical Behaviour of Orthopaedic Cement Loaded with Antibiotics in the Operation Room. Materiale Plastice, 54(2), 402-407. https://doi.org/10.37358/MP.17.2.4860

Harvard
Fleaca, R., Mitariu, S.I.C., Oleksik, V., Oleksik, M., Roman, M. (2017). 'Mechanical Behaviour of Orthopaedic Cement Loaded with Antibiotics in the Operation Room', Materiale Plastice, 54(2), pp. 402-407. https://doi.org/10.37358/MP.17.2.4860

IEEE
R. Fleaca, S.I.C. Mitariu, V. Oleksik, M. Oleksik, M. Roman, "Mechanical Behaviour of Orthopaedic Cement Loaded with Antibiotics in the Operation Room". Materiale Plastice, vol. 54, no. 2, pp. 402-407, 2017. [online]. https://doi.org/10.37358/MP.17.2.4860

Text
Radu Fleaca, Sebastian Ioan Cernusca Mitariu, Valentin Oleksik, Mihaela Oleksik, Mihai Roman,
Mechanical Behaviour of Orthopaedic Cement Loaded with Antibiotics in the Operation Room,
Materiale Plastice,
Volume 54, Issue 2,
2017,
Pages 402-407,
ISSN 2668-8220,
https://doi.org/10.37358/MP.17.2.4860.
(https://revmaterialeplastice.ro/Articles.asp?ID=4860)
Keywords: orthopaedic cement; polymethylmethacrylate; antibiotic; mechanical properties; periprostetic joint infection

RIS
TY - JOUR
T1 - Mechanical Behaviour of Orthopaedic Cement Loaded with Antibiotics in the Operation Room
A1 - Fleaca, Radu
A2 - Mitariu, Sebastian Ioan Cernusca
A3 - Oleksik, Valentin
A4 - Oleksik, Mihaela
A5 - Roman, Mihai
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2017
VL - 54
IS - 2
SP - 402
EP - 407
UR - https://doi.org/10.37358/MP.17.2.4860
KW - orthopaedic cement
KW - polymethylmethacrylate
KW - antibiotic
KW - mechanical properties
KW - periprostetic joint infection
ER -

BibTex
@article{MatPlast2017P402,
author = {Fleaca Radu and Mitariu Sebastian Ioan Cernusca and Oleksik Valentin and Oleksik Mihaela and Roman Mihai},
title = {Mechanical Behaviour of Orthopaedic Cement Loaded with Antibiotics in the Operation Room},
journal = {Materiale Plastice},
volume = {54},
number = {2},
pages = {402-407},
year = {2017},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.17.2.4860},
url = {https://revmaterialeplastice.ro/Articles.asp?ID=4860}
}

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