Formulation and Characterization of Antibacterial Hydrogels Based on Polyurethane Microstructures and 1,2,4-Triazole Derivatives

Moleriu, Lavinia; Duse, Adina Octavia; Borcan, Florin; Soica, Codruta; Kurunczi, Ludovic; Nicolov, Mirela; Mioc, Marius

Lavinia Moleriu, Adina Octavia Duse, Florin Borcan, Codruta Soica, Ludovic Kurunczi, Mirela Nicolov, Marius Mioc

Formulation and Characterization of Antibacterial Hydrogels Based on Polyurethane Microstructures and 1,2,4-Triazole Derivatives

Abstract:
Antibacterial gels offer an efficient hygiene in the absence of soap and water. The most part of these products are based on mixtures of different antibacterial and fungicide substances dissolved in an alcohol. Unfortunately, all cosmetic products containing alcohols wash the sebum and dry the skin. In the present study, alcohol-free antibacterial hydrogels were obtained through the synthesis of polyurethane (PU) microstructures with an increased amount of surfactant; 5-mercapto-1,2,4-triazole derivatives were used as active compounds inside the PU microstructures as antibacterial agents. There were studied: the pH of samples, the size and stability of PU microstructures, the skin irritation, sebum level and the hydration of stratum corneum using the mouse model and their efficiency against Escherichia coli. The results indicate that were obtained hydrogels with a slightly acid pH, PU microstructures with sizes between 185 and 265 nm and with a medium stability. It was found that these new antibacterial hydrogels do not produce an important modification of skin parameters (erythema, melanin, sebum and hydration of stratum corneum) and are efficient against E. coli.

Keywords:
E. coli; erythema; pH; sebum; stratum corneum

Issue: 2017 Volume 54, Issue 2

Pages: 348-352

Publication date: 2017/6/30

https://doi.org/10.37358/MP.17.2.4849

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This article is published under the Creative Commons Attribution 4.0 International License

Citation Styles

Cite this article as:
MOLERIU, L., DUSE, A.O., BORCAN, F., SOICA, C., KURUNCZI, L., NICOLOV, M., MIOC, M., Formulation and Characterization of Antibacterial Hydrogels Based on Polyurethane Microstructures and 1,2,4-Triazole Derivatives, Mater. Plast., 54(2), 2017, 348-352. https://doi.org/10.37358/MP.17.2.4849

Vancouver
Moleriu L, Duse AO, Borcan F, Soica C, Kurunczi L, Nicolov M, Mioc M. Formulation and Characterization of Antibacterial Hydrogels Based on Polyurethane Microstructures and 1,2,4-Triazole Derivatives. Mater. Plast.[internet]. 2017 Apr;54(2):348-352. Available from: https://doi.org/10.37358/MP.17.2.4849

APA 6th edition
Moleriu, L., Duse, A.O., Borcan, F., Soica, C., Kurunczi, L., Nicolov, M. & Mioc, M. (2017). Formulation and Characterization of Antibacterial Hydrogels Based on Polyurethane Microstructures and 1,2,4-Triazole Derivatives. Materiale Plastice, 54(2), 348-352. https://doi.org/10.37358/MP.17.2.4849

Harvard
Moleriu, L., Duse, A.O., Borcan, F., Soica, C., Kurunczi, L., Nicolov, M., Mioc, M. (2017). 'Formulation and Characterization of Antibacterial Hydrogels Based on Polyurethane Microstructures and 1,2,4-Triazole Derivatives', Materiale Plastice, 54(2), pp. 348-352. https://doi.org/10.37358/MP.17.2.4849

IEEE
L. Moleriu, A.O. Duse, F. Borcan, C. Soica, L. Kurunczi, M. Nicolov, M. Mioc, "Formulation and Characterization of Antibacterial Hydrogels Based on Polyurethane Microstructures and 1,2,4-Triazole Derivatives". Materiale Plastice, vol. 54, no. 2, pp. 348-352, 2017. [online]. https://doi.org/10.37358/MP.17.2.4849

Text
Lavinia Moleriu, Adina Octavia Duse, Florin Borcan, Codruta Soica, Ludovic Kurunczi, Mirela Nicolov, Marius Mioc,
Formulation and Characterization of Antibacterial Hydrogels Based on Polyurethane Microstructures and 1,2,4-Triazole Derivatives,
Materiale Plastice,
Volume 54, Issue 2,
2017,
Pages 348-352,
ISSN 2668-8220,
https://doi.org/10.37358/MP.17.2.4849.
(https://revmaterialeplastice.ro/Articles.asp?ID=4849)
Keywords: E. coli; erythema; pH; sebum; stratum corneum

RIS
TY - JOUR
T1 - Formulation and Characterization of Antibacterial Hydrogels Based on Polyurethane Microstructures and 1,2,4-Triazole Derivatives
A1 - Moleriu, Lavinia
A2 - Duse, Adina Octavia
A3 - Borcan, Florin
A4 - Soica, Codruta
A5 - Kurunczi, Ludovic
A6 - Nicolov, Mirela
A7 - Mioc, Marius
JF - Materiale Plastice
JO - Mater. Plast.
PB - Materiale Plastice SRL
SN - 2668-8220
Y1 - 2017
VL - 54
IS - 2
SP - 348
EP - 352
UR - https://doi.org/10.37358/MP.17.2.4849
KW - E. coli
KW - erythema
KW - pH
KW - sebum
KW - stratum corneum
ER -

BibTex
@article{MatPlast2017P348,
author = {Moleriu Lavinia and Duse Adina Octavia and Borcan Florin and Soica Codruta and Kurunczi Ludovic and Nicolov Mirela and Mioc Marius},
title = {Formulation and Characterization of Antibacterial Hydrogels Based on Polyurethane Microstructures and 1,2,4-Triazole Derivatives},
journal = {Materiale Plastice},
volume = {54},
number = {2},
pages = {348-352},
year = {2017},
issn = {2668-8220},
doi = {https://doi.org/10.37358/MP.17.2.4849},
url = {https://revmaterialeplastice.ro/Articles.asp?ID=4849}
}

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