SILVIU ADRIAN MARINESCU, CATALIN GHEORGHE BEJINARIU, CARMEN GIUGLEA RESEARCH RELATED TO BREAST IMPLANT-ASSOCIATED ANAPLASTIC LARGE CELL LYMPHOMA AND ITS INFLUENCE ON THE DECISION-MAKING PROCESS RELATED TO RECONSTRUCTIVE TECHNIQUES ANALYSIS OF A SERIES OF CASES AND LITERATURE REVIEW The worldwide increasing number of reports related to new cases of Breast Implant-associated Anaplastic Large Cell Lymphoma (BIA-ALCL) raises the interest of the scientific community in understanding the pathophysiology and the prognosis of these patients. This material presents the impact that BIA-ALCL exerts on the reconstructive options for patients who have undergone mastectomy. The research is based on data obtained from the analysis of a group of patients who have undergone 71 surgeries performed within the National Breast Reconstruction Program between 2015 and 2019. The statistical analysis revealed that 35.14% of the patients that were examined during the breast reconstruction consult refused the use of alloplastic techniques by invoking the potential associated risks described in the insufficient documentation of BIA-ALCL pathophysiology. Improving BIA-ALCL detection and reporting systems has led to an accelerated increase in the number of new diagnosed cases, determining the patientsí reticence towards the use of alloplastic reconstructive techniques.
Keywords: BIA-ALCL, siliconic implant, breast reconstruction, lymphoma