GABRIELA CIOCA, MARIANA PINTEALA, ELENA SIMONA BACAITA, IULIANA OPREA, IRINA CRUMPEI TANASA, SIMONA RUXANDRA VOLOVAT, VALENTIN STELIAN DRAGAN, SORIN TROCARU, CARMEN ANTON NONLINEAR BEHAVIORS IN GENE THERAPY THEORETICAL AND EXPERIMENTAL ASPECTS Gene therapy represents a promising method for treating genetic disorders or diseases consisting in the transfer of genetic material (DNA) to cells in order to substitute or to slow down the evolution of the defective gene in cells. Theoretical models to predict DNA release are difficult to build in the classical approach of continuous and differentiable physical quantities, due to the high number of interdependent phenomena that occur simultaneous. The article presents a theoretical model based on the fractal theory of motions in the form of Scale Relativity Theory to describe nonlinear behaviors in gene therapy. Correlations of the theoretical model with experimental data are also observed.
Keywords: gene therapy, nonlinearity, release, transfer of genetic material