BOGDAN ANDOR, JENEL M. PATRASCU, SORIN FLORESCU, DAN COJOCARU, MIHAI SANDESC, FLORIN BORCAN, OVIDIU BORUGA, SORIN BOLINTINEANU COMPARISON OF DIFFERENT KNEE IMPLANTS USED ON PATIENTS WITH OSTEOARTHRITIS CONTROL STUDY The field of cartilage repair and restoration has expanded a lot in the last decade since articular cartilage problems are very common. As a consequence, many biomaterials were created in order to aid physicians in treating different osteochondral defects. Polymers like polyurethanes or PGA-hyaluronan have been frequently used as the in vivo cartilage tissue repair solution, as reported in animal studies and in clinical applications. Three different implants (Agili-C, Hyalograft C, and Chondrotissue) were used in 23 patients (6 medial and 17 lateral lesions) in this study. Patients were assessed at 3, 6, 9, and 12 months postoperative follow-up visits using the International Knee Documentation Committee (IKDC) scores and Knee injury and Osteoarthritis Outcome Score (KOOS). The follow-up assessments demonstrated clinically and statistically significant improvements (p < 0.05) in all clinical outcome scores, as compared to the respective preoperative values: IKDC (48.9/77.1 for Chondrotissue implants), KOOS symptoms (58.2/71.9 for Agili-C implants), KOOS pain (54.8/66.1 for Agili-C implants), KOOS daily living activities (64.2/76.3 for Agili-C implants), KOOS sports (38.3/60.8 for Agili-C implants), KOOS quality of life (40.1/60.7 for Agili-C implants) demonstrating improvements in the case of implants previously mentioned. The overall results of this study support the successful use of the Agili-C, Chondrotissue and Hyalograft-C implants for the treatment of knee cartilage lesions.