GHEORGHE TOMOAIA, LACRIMIOARA-BIANCA POP, IOAN PETEAN, MARIA TOMOAIA-COTISEL SIGNIFICANCE OF SURFACE STRUCTURE ON ORTHOPEDIC MATERIALS The surface effect of nano- and microscale structures of some orthopedic materials, containing nano hydroxyapatite (HAP) and collagen type I (COL), on the interactions of osteoblasts with the surface of these materials is investigated and analyzed. The size and shape of inorganic particles are examined by TEM, SEM and AFM imaging. The surface morphology of collagen self-assemblies is also explored by AFM and SEM observations. Results show that the effect of the surface structure is significant on cell behaviour and can be correlated with cell constructs on these materials in cell culture.
Keywords: orthopedic materials, surface structure, osteoblasts, TEM, SEM, AFM