REVISTA DE MATERIALE PLASTICE

OANA CRACIUNESCU, LUCIA MOLDOVAN, CHRISTU TARDEI, GABRIELA SBARCEA
CARBODIIMIDE CROSS-LINKED NANOCOMPOSITE MATERIALS DESIGNED
FOR BONE TISSUE REGENERATION The paper presents the preparation of two new 3-D nanocomposite porous materials, based on collagen type I (COL) and b-tricalcium phosphate nanopowder (n-b-TCP) and the selection of the best method for their chemical cross-linking using 1-ethyl-3-(3-dimethyl aminopropyl)carbodiimide hydrochloride (EDC). To our knowledge, no EDC cross-linked COL/n-b-TCP composite materials for orthopedic use were reported. The physico-chemical and biological properties of the cross-linked composite materials were investigated by porosity, dissolution, enzymatic degradation and cytotoxicity analyses.

Key words: carbodiimide, nano-beta-tricalcium phosphate, collagen, cross-linking, biocompatibility

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Archive volume 2017 volume 2016 volume 2015 volume 2008 volume 2014 volume 2007 volume 2013 volume 2006 volume 2012 volume 2005 volume 2011 volume 2004 volume 2010 volume 2003 volume 2009 volume 2002	Edited by: SYSCOM 18 SRL SOCIETATEA DE CHIMIE DIN ROMANIA SC BIBLIOTECA CHIMIEI SA	Contact REVISTA DE MATERIALE PLASTICE Calea Plevnei Nr. 139B Sector 6, Bucuresti 060011 Tel/fax: 021 314 24 47 carmen.ioan@syscom18.com monica.baluta@syscom18.com